Q9CWK8: Sorting nexin-2

General Information

Protein names	- Sorting nexin-2
Gene names	Snx2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9CWK8

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAEREPPPL GDVKPTDFEE LEDGEDLFTS TVSTLESSPS SPEPASLPAE DISANSNGSK
        70         80         90        100        110        120
PVEVVLDDDR EDLFAEATEE VSLDSPEREL ILSSEPSPAV TPVTPTTLIA PRIESKSISA
       130        140        150        160        170        180
PVIFDRSRDE IEEEANGDIF DIEIGVSDPE KVGDGMNAYM AYRVTTKTSL SMFSKSEFSV
       190        200        210        220        230        240
KRRFSDFLGL HSKLASKYLH VGYIVPPAPE KSIVGMTKVK VGKEDSSSTE FVEKRRAALE
       250        260        270        280        290        300
RYLQRTVKHP TLLQDPDLRQ FLESSELPRA VNTQALSGAG ILRMVNKAAD AVNKMTIKMN
       310        320        330        340        350        360
ESDAWFEEKQ QQFENLDQQL RKLHASVEAL VCHRKELSAN TAAFAKSAAM LGNSEDHTAL
       370        380        390        400        410        420
SRALSQLAEV EEKIDQLHQE QAFADFYMFS ELLSDYIRLI AAVKGVFDHR MKCWQKWEDA
       430        440        450        460        470        480
QITLLKKRET EAKMMVANKP DKIQQAKNEI REWEAKVQQG ERDFEQISKT IRKEVGRFEK
       490        500        510
ERVKDFKAVI IKYLESLVQT QQQLIKYWEA FLPEAKAIA

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9CWK8-1-unknown	MAAERE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9CWK8-117-unmodified	SISAPV...	117		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q9CWK8-118-unknown	ISAPVI...	118	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34218
Q9CWK8-262-unknown	LESSEL...	262	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31041

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IESKSI	117	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34218
...DLRQFL	261	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31041
...AKAIA	519	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	117	SKSI.\|.ISAP	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	261	RQFL.\|.LESS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> SNX2_MOUSE @261

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)