Q9EPL8: Importin-7

General Information

Protein names	- Importin-7 - Imp7 - Ran-binding protein 7 - RanBP7
Gene names	Ipo7
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9EPL8

4 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDPNTIIEAL RGTMDPALRE AAERQLNEAH KSLNFVSTLL QITMSEQLDL PVRQAGVIYL
        70         80         90        100        110        120
KNMITQYWPD REATPGDIAP YTIPEEDRHC IRENIVEAII HSPELIRVQL TTCIHHIIKH
       130        140        150        160        170        180
DYPSRWTAIV DKIGFYLQSD NSACWLGILL CLYQLVKNYE YKKPEERSPL VAAMQHFLPV
       190        200        210        220        230        240
LKDRFIQLLS DQSDQSVLIQ KQIFKIFYAL VQYTLPLELI NQQNLTEWVE ILKTVVNRDV
       250        260        270        280        290        300
PNETLQVEED DRPELPWWKC KKWALHILAR LFERYGSPGN VSKEYNEFAE VFLKAFAVGV
       310        320        330        340        350        360
QQVLLKVLYQ YKEKQYMAPR VLQQTLNYIN QGVSHALTWK NLKPHIQGII QDVIFPLMCY
       370        380        390        400        410        420
TDADEELWQE DPYEYIRMKF DVFEDFISPT TAAQTLLFTA CSKRKEVLQK TMGFCYQILT
       430        440        450        460        470        480
EPNADPRKKD GALHMIGSLA EILLKKKIYK DQMEYMLQNH VFPLFSSELG YMRARACWVL
       490        500        510        520        530        540
HYFCEVKFKS DQNLQTALEL TRRCLIDDRE MPVKVEAAIA LQVLISNQEK AKEYITPFIR
       550        560        570        580        590        600
PVMQALLHII RETENDDLTN VIQKMICEYS EEVTPIAVEM TQHLAMTFNQ VIQTGPDEEG
       610        620        630        640        650        660
SDDKAVTAMG ILNTIDTLLS VVEDHKEITQ QLEGICLQVI GTVLQQHVLE FYEEIFSLAH
       670        680        690        700        710        720
SLTCQQVSPQ MWQLLPLVFE VFQQDGFDYF TDMMPLLHNY VTVDTDTLLS DTKYLEMIYS
       730        740        750        760        770        780
MCKKVLTGVA GEDAECHAAK LLEVIILQCK GRGIDQCIPL FVEAALERLT REVKTSELRT
       790        800        810        820        830        840
MCLQVAIAAL YYNPHLLLNT LENLRFPNNV EPVTNHFITQ WLNDVDCFLG LHDRKMCVLG
       850        860        870        880        890        900
LCALIDMEQI PQVLNQVSGQ ILPAFILLFN GLKRAYACHA EHENDSDDDE DAEDDDETEE
       910        920        930        940        950        960
LGSDEDDIDE DGQEYLEILA KQAGEDGDDE DWEEDDAEET ALEGYSTIID DEDNPVDEYQ
       970        980        990       1000       1010       1020
IFKAIFQTIQ NRNPVWYQAL THGLNEEQRK QLQDIATLAD QRRAAHESKM IEKHGGYKFS
      1030
APVVPSSFNF GGPAPGMN

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9EPL8-1-Acetylation	MDPNTI...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9EPL8-772-unknown	EVKTSE...	772		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31132
Q9EPL8-977-unknown	YQALTH...	977		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34298
Q9EPL8-980-unknown	LTHGLN...	980		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34299

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ERLTRE	771	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31132
...RNPVWY	976	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34298
...VWYQAL	979	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34299
...APGMN	1038	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	771	LTRE.\|.EVKT	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> IPO7_MOUSE @771
MMP2_MOUSE	976	PVWY.\|.YQAL	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
MMP2_MOUSE	979	YQAL.\|.LTHG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)