Q9EQK5: Major vault protein

General Information

Protein names	- Major vault protein - MVP
Gene names	Mvp
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9EQK5

5 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATEEAIIRI PPYHYIHVLD QNSNVSRVEV GPKTYIRQDN ERVLFAPVRM VTVPPRHYCI
        70         80         90        100        110        120
VANPVSRDAQ SSVLFDVTGQ VRLRHADQEI RLAQDPFPLY PGELLEKDIT PLQVVLPNTA
       130        140        150        160        170        180
LHLKALLDFE DKNGDKVMAG DEWLFEGPGT YIPQKEVEVV EIIQATVIKQ NQALRLRARK
       190        200        210        220        230        240
ECFDRDGKER VTGEEWLVRS VGAYLPAVFE EVLDLVDAVI LTEKTALHLR ARQNFKDLRG
       250        260        270        280        290        300
VAHRTGEEWL VTVQDTEAHV PDVYEEVLGV VPITTLGPRH YCVILDPMGP DGKNQLGQKR
       310        320        330        340        350        360
VVKGEKSFFL QPGERLERGI QDVYVLSEQQ GLLLKALQPL EEGEGEEKVA HQAGDRWLIR
       370        380        390        400        410        420
GPLEYVPSAK VEVVEERQAI PLDQNEGIYV QDVKTGKVRA VIGSTYMLTQ DEVLWEKELP
       430        440        450        460        470        480
SGVEELLNLG HDPLADRGQK GTAKVLQPSA ARNKTRVVSY RVPHNAAVQV YDYRAKRARV
       490        500        510        520        530        540
VFGPELVSLD PEEQFTVLSL SAGRPKRPHA RRALCLLLGP DFFTDVITIE TADHARLQLQ
       550        560        570        580        590        600
LAYNWHFELK NRNDPEETAK LFSVPDFVGD ACKAIASRVR GAVASVTFDD FHKNSARIIR
       610        620        630        640        650        660
MAVFGFEMSE DAGPDGALLP RARDRAVFPQ NGLVVSSVDV QSVEPVDQRT RDALQRSVQL
       670        680        690        700        710        720
AIEITTNSQE AAAKHEAQRL EQEARGRLER QKILDQSEAE KARKELLELE AMSMAVESTG
       730        740        750        760        770        780
NAKAEAESRA EAARIEGEGS VLQAKLKAQA LAIETEAELE RVKKVREMEL IYSRAQLELE
       790        800        810        820        830        840
VSKAQQLADV EAKKFKEMTE ALGPGTIRDL AVAGPEMQVK LLQSLGLKST LITDGSSPIN
       850        860
LFNTAFGLLG LGSDGQPPVQ K

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9EQK5-2-unknown	MATEEA...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9EQK5-2-unknown	MATEEA...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9EQK5-2-Acetylation	ATEEAI...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9EQK5-2-Acetylation	ATEEAI...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9EQK5-75-unknown	FDVTGQ...	75		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31135
Q9EQK5-390-unknown	VQDVKT...	390		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31136
Q9EQK5-715-unknown	AVESTG...	715		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31137
Q9EQK5-715-unknown	AVESTG...	715		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29380

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QSSVLF	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31135
...NEGIYV	389	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31136
...EAMSMA	714	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31137
...EAMSMA	714	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29380
...PPVQK	861	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	74	SVLF.\|.FDVT	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> MVP_MOUSE @74
CATE_MOUSE	389	GIYV.\|.VQDV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> MVP_MOUSE @389
CATE_MOUSE	714	MSMA.\|.AVES	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> MVP_MOUSE @714
CATD_MOUSE	714	MSMA.\|.AVES	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> MVP_MOUSE @714

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)