Q9EQU5: Protein SET

General Information

Protein names	- Protein SET - Phosphatase 2A inhibitor I2PP2A - I-2PP2A - Template-activating factor I - TAF-I
Gene names	Set
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9EQU5

7 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Protein SET - Isoform 3 of Protein SET

Sequence View

        10         20         30         40         50         60
MAPKRQSAIL PQPKKPRPAA APKLEDKSAS PGLPKGEKEQ QEAIEHIDEV QNEIDRLNEQ
        70         80         90        100        110        120
ASEEILKVEQ KYNKLRQPFF QKRSELIAKI PNFWVTTFVN HPQVSALLGE EDEEALHYLT
       130        140        150        160        170        180
RVEVTEFEDI KSGYRIDFYF DENPYFENKV LSKEFHLNES GDPSSKSTEI KWKSGKDLTK
       190        200        210        220        230        240
RSSQTQNKAS RKRQHEEPES FFTWFTDHSD AGADELGEVI KDDIWPNPLQ YYLVPDMDDE
       250        260        270        280
EGEAEDDDDD DEEEEGLEDI DEEGDEDEGE EDDDEDEGEE GEEDEGEDD         10         20         30         40         50         60
MAPKRQSAIL PQPKKPRPAA APKLEDKSAS PGLPKGEKEQ QEAIEHIDEV QNEIDRLNEQ
        70         80         90        100        110        120
ASEEILKVEQ KYNKLRQPFF QKRSELIAKI PNFWVTTFVN HPQVSALLGE EDEEALHYLT
       130        140        150        160        170        180
RVEVTEFEDI KSGYRIDFYF DENPYFENKV LSKEFHLNES GDPSSKSTEI KWKSGKDLTK
       190        200        210        220        230        240
RSSQTQNKAS RKRQHEEPES FFTWFTDHSD AGADELGEVI KDDIWPNPLQ YYLVPDMDDE
       250        260        270        280
EGEAEDDDDD DEEEEGLEDI DEEGDEDEGE EDDDEDEGEE GEEDEGEDD

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9EQU5-1-unknown	MAPKRQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89374
Q9EQU5-2-unknown	MAPKRQ...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9EQU5-2-N,N,N-trimethylalanine	APKRQS...	2	methylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9EQU5-2-N,N,N-trimethylalanine	APKRQS...	2	methylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110753
Q9EQU5-6-unknown	QSAILP...	6		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34300
Q9EQU5-6-unknown	QSAILP...	6		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt194740
Q9EQU5-32-unknown	GLPKGE...	32		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34301
Q9EQU5-32-unknown	GLPKGE...	32		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137759
Q9EQU5-101-unknown	HPQVSA...	101		inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q9EQU5-101-unknown	HPQVSA...	101		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196975
Q9EQU5-107-unknown	LLGEED...	107		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34303
Q9EQU5-107-unknown	LLGEED...	107		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142099

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MAPKRQ	5	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34300
...KSASPG	31	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34301
...KSASPG	31	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120758
...PQVSAL	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34303
...PQVSAL	106	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125284
...EGEDD	289	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EGEDD	289	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84991

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	5	PKRQ.\|.QSAI	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> SET_MOUSE @5
MMP2_MOUSE	31	ASPG.\|.GLPK	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
MMP2_MOUSE	106	VSAL.\|.LLGE	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)