Q9H0E2: Toll-interacting protein

General Information

Protein names	- Toll-interacting protein
Gene names	TOLLIP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H0E2

4 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATTVSTQRG PVYIGELPQD FLRITPTQQQ RQVQLDAQAA QQLQYGGAVG TVGRLNITVV
        70         80         90        100        110        120
QAKLAKNYGM TRMDPYCRLR LGYAVYETPT AHNGAKNPRW NKVIHCTVPP GVDSFYLEIF
       130        140        150        160        170        180
DERAFSMDDR IAWTHITIPE SLRQGKVEDK WYSLSGRQGD DKEGMINLVM SYALLPAAMV
       190        200        210        220        230        240
MPPQPVVLMP TVYQQGVGYV PITGMPAVCS PGMVPVALPP AAVNAQPRCS EEDLKAIQDM
       250        260        270
FPNMDQEVIR SVLEAQRGNK DAAINSLLQM GEEP

Isoforms

- Isoform 2 of Toll-interacting protein

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9H0E2-2-unknown	MATTVS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H0E2-2-Acetylation	ATTVST...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H0E2-2-Acetylation	ATTVST...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9H0E2-2-Acetylation	ATTVST...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9H0E2-37-	AQAAQQ...	37			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9H0E2-70-unknown	MTRMDP...	70		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000434035

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...EDLKAI	236	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000434494
...MGEEP	274	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...MGEEP	274		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)