TopFIND 4.0

Q9H160: Inhibitor of growth protein 2

General Information

Protein names
- Inhibitor of growth protein 2
- Inhibitor of growth 1-like protein
- ING1Lp
- p32
- p33ING2
Gene names ING2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9H160

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLGQQQQQLY SSAALLTGER SRLLTCYVQD YLECVESLPH DMQRNVSVLR ELDNKYQETL 
        70         80         90        100        110        120 
KEIDDVYEKY KKEDDLNQKK RLQQLLQRAL INSQELGDEK IQIVTQMLEL VENRARQMEL 
       130        140        150        160        170        180 
HSQCFQDPAE SERASDKAKM DSSQPERSSR RPRRQRTSES RDLCHMANGI EDCDDQPPKE 
       190        200        210        220        230        240 
KKSKSAKKKK RSKAKQEREA SPVEFAIDPN EPTYCLCNQV SYGEMIGCDN EQCPIEWFHF 
       250        260        270        280    
SCVSLTYKPK GKWYCPKCRG DNEKTMDKST EKTKKDRRSR 

Isoforms

- Isoform ING2b of Inhibitor of growth protein 2

Sequence View

        10         20         30         40         50         60 
MLGQQQQQLY SSAALLTGER SRLLTCYVQD YLECVESLPH DMQRNVSVLR ELDNKYQETL 
        70         80         90        100        110        120 
KEIDDVYEKY KKEDDLNQKK RLQQLLQRAL INSQELGDEK IQIVTQMLEL VENRARQMEL 
       130        140        150        160        170        180 
HSQCFQDPAE SERASDKAKM DSSQPERSSR RPRRQRTSES RDLCHMANGI EDCDDQPPKE 
       190        200        210        220        230        240 
KKSKSAKKKK RSKAKQEREA SPVEFAIDPN EPTYCLCNQV SYGEMIGCDN EQCPIEWFHF 
       250        260        270        280    
SCVSLTYKPK GKWYCPKCRG DNEKTMDKST EKTKKDRRSR 



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9H160-1- MLGQQQ... 1 Subtiligase Based Positive Selection Wells apoptotic_Jurkat_staurotrail 23264352
    Q9H160-1-unknown MLGQQQ... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DRRSR 280 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...DRRSR 280 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73515

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)