Q9HCM1: Retroelement silencing factor 1 {ECO:0000305}

General Information

Protein names	- Retroelement silencing factor 1 {ECO:0000305}
Gene names	KIAA1551
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9HCM1

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNWNEKPKSA TLPPLYPKSQ PPFLHQSLIN QITTTSQSSF SYPGSNQEAC MYPGNSNPIS
        70         80         90        100        110        120
QPLLNIQNYP QQISVSDMHN GTVVASHTSV ERITYANVNG PKQLTHNLQM SSGVTQNVWL
       130        140        150        160        170        180
NSPMRNPVHS HIGATVSHQT DFGANVPNMP ALQSQLITSD TYSMQMQMIP SNSTRLPVAY
       190        200        210        220        230        240
QGNQGLNQSF SEQQVDWTQQ CISKGLTYPD YRPPPKLYRY SPQSFLPDST IQKQNFIPHT
       250        260        270        280        290        300
SLQVKNSQLL NSVLTLPSRQ TSAVPSQQYA TQTDKRPPPP PYNCRYGSQP LQSTQHITKH
       310        320        330        340        350        360
LSMEVPQSRE MLSSEIRTSF QQQWQNPNEN VSTIGNFTNL KVNTNSKQPF NSPIRSSVDG
       370        380        390        400        410        420
VQTLAQTNEE KIMDSCNPTS NQVLDTSVAK EKLVRDIKTL VEIKQKFSEL ARKIKINKDL
       430        440        450        460        470        480
LMAAGCIKMT NTSYSEPAQN SKLSLKQTAK IQSGPQITPV MPENAERQTP TVVESAETNK
       490        500        510        520        530        540
TQCMLNSDIQ EVNCRRFNQV DSVLPNPVYS EKRPMPDSSH DVKVLTSKTS AVEMTQAVLN
       550        560        570        580        590        600
TQLSSENVTK VEQNSPAVCE TISVPKSMST EEYKSKIQNE NMLLLALLSQ ARKTQKTVLK
       610        620        630        640        650        660
DANQTIQDSK PDSCEMNPNT QMTGNQLNLK NMETPSTSNV SGRVLDNSFC SGQESSTKGM
       670        680        690        700        710        720
PAKSDSSCSM EVLATCLSLW KKQPSDTAKE KECDKLRTNT TAVGISKPAN IHVKSPCSVV
       730        740        750        760        770        780
GNSNSQNKIS NPSQQTALSM VMHNYESSGI NITKGTELQI AVVSPLVLSE VKTLSVKGIT
       790        800        810        820        830        840
PAVLPETVYP VIKEGSVCSL QNQLAENAKA TAALKVDVSG PVASTATSTK IFPLTQKEKQ
       850        860        870        880        890        900
NESTNGNSEV TPNVNQGKHN KLESAIHSPM NDQQISQESR NSTVVSSDTL QIDNICSLVE
       910        920        930        940        950        960
GDTSYNSQIA KIFSSLPLKM VEPQKPSLPN QQGIGSREPE KQLDNTTENK DFGFQKDKPV
       970        980        990       1000       1010       1020
QCTDVSHKIC DQSKSEPPLE SSFNNLETNR VILEKSSLEH ATEKSTANDT CSSAAIQEDI
      1030       1040       1050       1060       1070       1080
YPQEIDASSN YTPQDPARNE IHSDKAPVLY LHDQLSELLK EFPYGIEAVN TREGSVGQQT
      1090       1100       1110       1120       1130       1140
TYQTSEDQTA DKTSSDSKDP ADQIQITILS SEQMKEIFPE QDDQPYVVDK LAEPQKEEPI
      1150       1160       1170       1180       1190       1200
TEVVSQCDLQ APAAGQSRDS VILDSEKDDI HCCALGWLSM VYEGVPQCQC NSIKNSSSEE
      1210       1220       1230       1240       1250       1260
EKQKEQCSPL DTNSCKQGER TSDRDVTVVQ FKSLVNNPKT PPDGKSHFPE LQDDSRKDTP
      1270       1280       1290       1300       1310       1320
KTKHKSLPRT EQELVAGQFS SKCDKLNPLQ NHKRKKLRFH EVTFHSSNKM TASYEQASQE
      1330       1340       1350       1360       1370       1380
TRQKKHVTQN SRPLKTKTAF LPNKDVYKKH SSLGQSLSPE KIKLKLKSVS FKQKRKLDQG
      1390       1400       1410       1420       1430       1440
NVLDMEVKKK KHDKQEQKGS VGATFKLGDS LSNPNERAIV KEKMVSNTKS VDTKASSSKF
      1450       1460       1470       1480       1490       1500
SRILTPKEYL QRQKHKEALS NKASKKICVK NVPCDSEHMR PSKLAVQVES CGKSNEKHSS
      1510       1520       1530       1540       1550       1560
GVQTSKESLN GLTSHGKNLK IHHSQESKTY NILRNVKEKV GGKQPDKIWI DKTKLDKLTN
      1570       1580       1590       1600       1610       1620
ISNEAQFSQM PPQVKDQKKL YLNRVGFKCT ERESISLTKL ESSPRKLHKD KRQENKHKTF
      1630       1640       1650       1660       1670       1680
LPVKGNTEKS NMLEFKLCPD ILLKNTNSVE ERKDVKPHPR KEQAPLQVSG IKSTKEDWLK
      1690       1700       1710       1720       1730       1740
FVATKKRTQK DSQERDNVNS RLSKRSFSAD GFEMLQNPVK DSKEMFQTYK QMYLEKRSRS

LGSSPVK

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9HCM1-1-unknown	MNWNEK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9HCM1-360-	GVQTLA...	360		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9HCM1-360-	GVQTLA...	360		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9HCM1-360-	GVQTLA...	360		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QITTTS	35	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000445152
...MEVLAT	674	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000370442
...SSPVK	1747	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)