Q9JI91: Alpha-actinin-2
Protein names | - Alpha-actinin-2 - Alpha-actinin skeletal muscle isoform 2 - F-actin cross-linking protein |
---|---|
Gene names | Actn2 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9JI91 |
3
N-termini
3
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MNQIEPGVQY NYVYDEDEYM IQEEEWDRDL LLDPAWEKQQ RKTFTAWCNS HLRKAGTQIE
70 80 90 100 110 120
NIEEDFRNGL KLMLLLEVIS GERLPKPDRG KMRFHKIANV NKALDYIASK GVKLVSIGAE
130 140 150 160 170 180
EIVDGNVKMT LGMIWTIILR FAIQDISVEE TSAKEGLLLW CQRKTAPYRN VNIQNFHTSW
190 200 210 220 230 240
KDGLGLCALI HRHRPDLIDY SKLNKDDPIG NINLAMEIAE KHLDIPKMLD AEDIVNTPKP
250 260 270 280 290 300
DERAIMTYVS CFYHAFAGAE QAETAANRIC KVLAVNQENE RLMEEYERLA SELLEWIRRT
310 320 330 340 350 360
IPWLENRTPE KTMQAMQKKL EDFRDYRRKH KPPKVQEKCQ LEINFNTLQT KLRISNRPAF
370 380 390 400 410 420
MPSEGKMVSD IAGAWQRLEQ AEKGYEEWLL NEIRRLERLE HLAEKFRQKA STHETWAYGK
430 440 450 460 470 480
EQILLQKDYE SASLTEVRAL LRKHEAFESD LAAHQDRVEQ IAAIAQELNE LDYHDAVNVN
490 500 510 520 530 540
DRCQKICDQW DRLGTLTQKR REALERTEKL LETIDQLHLE FAKRAAPFNN WMEGAMEDLQ
550 560 570 580 590 600
DMFIVHSIEE IQSLITAHEQ FKATLPEADG ERQSILAIQN EVEKVIQSYS IRISSSNPYS
610 620 630 640 650 660
TVTMDELRNK WDKVKQLVPV RDQSLQEELA RQHANERLRR QFAAQANAIG PWIQNKMEEI
670 680 690 700 710 720
ARSSIQITGA LEDQMNQLKQ YEHNIINYKN NIDKLEGDHQ LIQEALVFDN KHTNYTMEHI
730 740 750 760 770 780
RVGWELLLTT IARTINEVET QILTRDAKGI TQEQMNEFRA SFNHFDRRKN GLMDHEDFRA
790 800 810 820 830 840
CLISMGYDLG EAEFARIMTL VDPNGQGTVT FQSFIDFMTR ETADTDTAEQ VIASFRILAS
850 860 870 880 890
DKPYILAEEL RRELPPDQAQ YCIKRMPPYS GPGSVPGALD YTAFSSALYG ESDL
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9JI91-1-unknown | MNQIEP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9JI91-342-unknown | EINFNT... | 342 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31173 | |||
Q9JI91-346-unknown | NTLQTK... | 346 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31174 | |||
Q9JI91-346-unknown | NTLQTK... | 346 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29387 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EKCQLE | 341 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31173 | |||
...LEINFN | 345 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31174 | |||
...LEINFN | 345 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29387 | |||
...GESDL | 894 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 341 | CQLE.|.EINF | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> ACTN2_MOUSE @341 | ||
CATE_MOUSE | 345 | INFN.|.NTLQ | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> ACTN2_MOUSE @345 | ||
CATD_MOUSE | 345 | INFN.|.NTLQ | inferred from experiment | unknown | MEROPS | Zornig M | Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009) | 22388353, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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