Q9JLJ2: 4-trimethylaminobutyraldehyde dehydrogenase

General Information

Protein names	- 4-trimethylaminobutyraldehyde dehydrogenase - TMABA-DH - TMABADH - 1.2.1.47 {ECO:0000250\|UniProtKB:P49189} - Aldehyde dehydrogenase family 9 member A1 - 1.2.1.3 {ECO:0000250\|UniProtKB:P49189}
Gene names	Aldh9a1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9JLJ2

7 N-termini

5 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSTGTFVVSQ PLNYRGGARV EPVDASGTEK AFEPATGRVI ATFACSGEKE VNLAVENAKA
        70         80         90        100        110        120
AFKLWSKKSG LERCQVLLEA ARIIKERKDE IATVETINNG KSIFEARLDV DTCWQCLEYY
       130        140        150        160        170        180
AGLAASMAGE HIQLPGGSFG YTRREPLGVC VGIGAWNYPF QIACWKSAPA LACGNAMIFK
       190        200        210        220        230        240
PSPFTPVSAL LLAEIYTKAG APPGLFNVVQ GGAATGQFLC HHREVAKISF TGSVPTGVKI
       250        260        270        280        290        300
MEMSAKGVKP ITLELGGKSP LIIFSDCNME NAVKGALMAN FLTQGQVCCN GTRVFVQKEI
       310        320        330        340        350        360
ADKFINEVVK QTQKIKLGDP LLEDTRMGPL INAPHLERVL GFVKLAKEQG ATVLCGGEVY
       370        380        390        400        410        420
VPEDPKLKHG YYMTPCILTN CRDDMTCVKE EIFGPVMSIL TFGTEAEVLE RANDTTFGLA
       430        440        450        460        470        480
AGVFTRDIQR AHRVAAELQA GTCYINNYNV SPVELPFGGY KKSGFGRENG RVTIEYYSQL
       490
KTVCVEMGDV ESAF

Isoforms

Sequence View

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Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 5 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9JLJ2-2-unknown	MSTGTF...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9JLJ2-2-unknown	MSTGTF...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9JLJ2-2-Acetylation	STGTFV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9JLJ2-2-Acetylation	STGTFV...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9JLJ2-7-unknown	VVSQPL...	7		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29398
Q9JLJ2-7-unknown	VVSQPL...	7		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31200
Q9JLJ2-91-unknown	IATVET...	91		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31201
Q9JLJ2-94-unknown	VETINN...	94		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31202
Q9JLJ2-308-unknown	VVKQTQ...	308		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29399
Q9JLJ2-308-unknown	VVKQTQ...	308		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31203
Q9JLJ2-315-unmodified	IKLGDP...	315			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...STGTFV	6	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29398
...STGTFV	6	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31200
...ERKDEI	90	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31201
...DEIATV	93	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31202
...KFINEV	307	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29399
...KFINEV	307	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31203
...VESAF	494	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATD_MOUSE	6	GTFV.\|.VVSQ	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> AL9A1_MOUSE @6
CATE_MOUSE	6	GTFV.\|.VVSQ	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> AL9A1_MOUSE @6
CATE_MOUSE	90	KDEI.\|.IATV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> AL9A1_MOUSE @90
CATE_MOUSE	93	IATV.\|.VETI	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> AL9A1_MOUSE @93
CATD_MOUSE	307	INEV.\|.VVKQ	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> AL9A1_MOUSE @307
CATE_MOUSE	307	INEV.\|.VVKQ	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> AL9A1_MOUSE @307

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)