Q9NWY4: Histone PARylation factor 1 {ECO:0000303|PubMed:27067600, ECO:0000312|HGNC:HGNC:26051}

General Information

Protein names	- Histone PARylation factor 1 {ECO:0000303\|PubMed:27067600, ECO:0000312\|HGNC:HGNC:26051}
Gene names	C4orf27
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NWY4

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVGGGGKRRP GGEGPQCEKT TDVKKSKFCE ADVSSDLRKE VENHYKLSLP EDFYHFWKFC
        70         80         90        100        110        120
EELDPEKPSD SLSASLGLQL VGPYDILAGK HKTKKKSTGL NFNLHWRFYY DPPEFQTIII
       130        140        150        160        170        180
GDNKTQYHMG YFRDSPDEFP VYVGINEAKK NCIIVPNGDN VFAAVKLFLT KKLREITDKK
       190        200        210        220        230        240
KINLLKNIDE KLTEAARELG YSLEQRTVKM KQRDKKVVTK TFHGAGLVVP VDKNDVGYRE
       250        260        270        280        290        300
LPETDADLKR ICKTIVEAAS DEERLKAFAP IQEMMTFVQF ANDECDYGMG LELGMDLFCY
       310        320        330        340
GSHYFHKVAG QLLPLAYNLL KRNLFAEIIE EHLANRSQEN IDQLAA

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

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Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NWY4-1-Acetylation	MVGGGG...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NWY4-1-Acetylation	MVGGGG...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9NWY4-1-Acetylation	MVGGGG...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9NWY4-2-unknown	VGGGGK...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9NWY4-224-unknown	GAGLVV...	224		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6818

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...TKTFHG	223	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6818
...DQLAA	346	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...DQLAA	346		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...DQLAA	346		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	223	TFHG.\|.GAGL	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)