Q9NXE8: Pre-mRNA-splicing factor CWC25 homolog

General Information

Protein names	- Pre-mRNA-splicing factor CWC25 homolog - Coiled-coil domain-containing protein 49 - Spliceosome-associated protein homolog CWC25
Gene names	CWC25
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NXE8

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGGGDLNLKK SWHPQTLRNV EKVWKAEQKH EAERKKIEEL QRELREERAR EEMQRYAEDV
        70         80         90        100        110        120
GAVKKKEEKL DWMYQGPGGM VNRDEYLLGR PIDKYVFEKM EEKEAGCSSE TGLLPGSIFA
       130        140        150        160        170        180
PSGANSLLDM ASKIREDPLF IIRKKEEEKK REVLNNPVKM KKIKELLQMS LEKKEKKKKK
       190        200        210        220        230        240
EKKKKHKKHK HRSSSSDRSS SEDEHSAGRS QKKMANSSPV LSKVPGYGLQ VRNSDRNQGL
       250        260        270        280        290        300
QGPLTAEQKR GHGMKNHSRS RSSSHSPPRH ASKKSTREAG SRDRRSRSLG RRSRSPRPSK
       310        320        330        340        350        360
LHNSKVNRRE TGQTRSPSPK KEVYQRRHAP GYTRKLSAEE LERKRQEMME NAKWREEERL
       370        380        390        400        410        420
NILKRHAKDE EREQRLEKLD SRDGKFIHRM KLESASTSSL EDRVKRNIYS LQRTSVALEK

NFMKR

Isoforms

- Isoform 2 of Pre-mRNA-splicing factor CWC25 homolog

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NXE8-1-unknown	MGGGDL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NXE8-2-	GGGDLN...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9NXE8-2-	GGGDLN...	2		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9NXE8-2-	GGGDLN...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9NXE8-348-unknown	MMENAK...	348	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt72179

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...NFMKR	425	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...NFMKR	425	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt67797

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)