TopFIND 4.0

Q9P2T1: GMP reductase 2 {ECO:0000255|HAMAP-Rule:MF_03195}

General Information

Protein names
- GMP reductase 2 {ECO:0000255|HAMAP-Rule:MF_03195}
- GMPR 2 {ECO:0000255|HAMAP-Rule:MF_03195}
- 1.7.1.7 {ECO:0000255|HAMAP-Rule:MF_03195}
- Guanosine 5'-monophosphate oxidoreductase 2 {ECO:0000255|HAMAP-Rule:MF_03195}
- Guanosine monophosphate reductase 2 {ECO:0000255|HAMAP-Rule:MF_03195}

Gene names GMPR2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9P2T1

5

N-termini

7

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPHIDNDVKL DFKDVLLRPK RSTLKSRSEV DLTRSFSFRN SKQTYSGVPI IAANMDTVGT 
        70         80         90        100        110        120 
FEMAKVLCKF SLFTAVHKHY SLVQWQEFAG QNPDCLEHLA ASSGTGSSDF EQLEQILEAI 
       130        140        150        160        170        180 
PQVKYICLDV ANGYSEHFVE FVKDVRKRFP QHTIMAGNVV TGEMVEELIL SGADIIKVGI 
       190        200        210        220        230        240 
GPGSVCTTRK KTGVGYPQLS AVMECADAAH GLKGHIISDG GCSCPGDVAK AFGAGADFVM 
       250        260        270        280        290        300 
LGGMLAGHSE SGGELIERDG KKYKLFYGMS SEMAMKKYAG GVAEYRASEG KTVEVPFKGD 
       310        320        330        340    
VEHTIRDILG GIRSTCTYVG AAKLKELSRR TTFIRVTQQV NPIFSEAC

Isoforms

- Isoform 2 of GMP reductase 2 - Isoform 3 of GMP reductase 2

Sequence View

        10         20         30         40         50         60 
MPHIDNDVKL DFKDVLLRPK RSTLKSRSEV DLTRSFSFRN SKQTYSGVPI IAANMDTVGT 
        70         80         90        100        110        120 
FEMAKVLCKF SLFTAVHKHY SLVQWQEFAG QNPDCLEHLA ASSGTGSSDF EQLEQILEAI 
       130        140        150        160        170        180 
PQVKYICLDV ANGYSEHFVE FVKDVRKRFP QHTIMAGNVV TGEMVEELIL SGADIIKVGI 
       190        200        210        220        230        240 
GPGSVCTTRK KTGVGYPQLS AVMECADAAH GLKGHIISDG GCSCPGDVAK AFGAGADFVM 
       250        260        270        280        290        300 
LGGMLAGHSE SGGELIERDG KKYKLFYGMS SEMAMKKYAG GVAEYRASEG KTVEVPFKGD 
       310        320        330        340    
VEHTIRDILG GIRSTCTYVG AAKLKELSRR TTFIRVTQQV NPIFSEAC         10         20         30         40         50         60 
MPHIDNDVKL DFKDVLLRPK RSTLKSRSEV DLTRSFSFRN SKQTYSGVPI IAANMDTVGT 
        70         80         90        100        110        120 
FEMAKVLCKF SLFTAVHKHY SLVQWQEFAG QNPDCLEHLA ASSGTGSSDF EQLEQILEAI 
       130        140        150        160        170        180 
PQVKYICLDV ANGYSEHFVE FVKDVRKRFP QHTIMAGNVV TGEMVEELIL SGADIIKVGI 
       190        200        210        220        230        240 
GPGSVCTTRK KTGVGYPQLS AVMECADAAH GLKGHIISDG GCSCPGDVAK AFGAGADFVM 
       250        260        270        280        290        300 
LGGMLAGHSE SGGELIERDG KKYKLFYGMS SEMAMKKYAG GVAEYRASEG KTVEVPFKGD 
       310        320        330        340    
VEHTIRDILG GIRSTCTYVG AAKLKELSRR TTFIRVTQQV NPIFSEAC



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

5 N-termini - 7 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)