Q9QXV0: ProSAAS

General Information

Protein names	- ProSAAS - IA-4 - Proprotein convertase subtilisin/kexin type 1 inhibitor - Proprotein convertase 1 inhibitor - pro-SAAS - KEP - Big SAAS - b-SAAS - Little SAAS - l-SAAS - Big PEN-LEN - b-PEN-LEN - SAAS CT(1-49) - PEN - PEN-20 - PEN-19 - Little LEN - l-LEN - Big LEN - b-LEN - SAAS CT(25-40)
Gene names	Pcsk1n
Organism	Mus musculus
Protease Family
Protease ID	I49.001
Chromosome location
UniProt ID	Q9QXV0

9 N-termini

9 C-termini

11 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGSPLLCGP RAGGVGILVL LLLGLLRLPP TLSARPVKEP RSLSAASAPL VETSTPLRLR
        70         80         90        100        110        120
RAVPRGEAAG AVQELARALA HLLEAERQER ARAEAQEAED QQARVLAQLL RAWGSPRASD
       130        140        150        160        170        180
PPLAPDDDPD APAAQLARAL LRARLDPAAL AAQLVPAPAA APRPRPPVYD DGPTGPDVED
       190        200        210        220        230        240
AGDETPDVDP ELLRYLLGRI LTGSSEPEAA PAPRRLRRSV DQDLGPEVPP ENVLGALLRV
       250
KRLENPSPQA PARRLLPP

Isoforms

Sequence View

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9QXV0-34-unknown	ARPVKE...	34	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9QXV0-42-unknown	SLSAAS...	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34741
Q9QXV0-59-unknown	LRRAVP...	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31497
Q9QXV0-59-unknown	LRRAVP...	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34742
Q9QXV0-59-unknown	LRRAVP...	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31460
Q9QXV0-62-unknown	AVPRGE...	62	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34743
Q9QXV0-66-unknown	GEAAGA...	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34744
Q9QXV0-91-unknown	ARAEAQ...	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34745
Q9QXV0-238-unknown	LRVKRL...	238	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31461
Q9QXV0-240-unknown	VKRLEN...	240	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31498
Q9QXV0-240-unknown	VKRLEN...	240	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31462
Q9QXV0-243-unknown	LENPSP...	243	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34746

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VKEPRS	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34741
...STPLRL	58	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31497
...STPLRL	58	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34742
...STPLRL	58	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31460
...LRLRRA	61	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34743
...RAVPRG	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34744
...ERQERA	90	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34745
...VLGALL	237	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31461
...GALLRV	239	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31498
...GALLRV	239	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31462
...LRVKRL	242	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34746
...RLLPP	258	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
NEC2_MOUSE	41	EPRS.\|.SLSA	inferred from experiment	unknown	MEROPS	Fricker LD	Pan H et al.:The role of prohormone converta... (S08.073)	16903874,
CBPA6_MOUSE	58	PLRL.\|.LRRA	inferred from experiment	unknown	MEROPS	Fricker LD	Lyons PJ et al.:Characterization of carboxypept... (M14.018)	18178555,
NEC2_MOUSE	58	PLRL.\|.LRRA	inferred from experiment	unknown	MEROPS	Fricker LD	Pan H et al.:The role of prohormone converta... (S08.073)	16903874,
CBPA4_MOUSE	58	PLRL.\|.LRRA	inferred from experiment	unknown	MEROPS	Fricker LD	Tanco S et al.:Characterization of the substra... (M14.017)	20385563,
NEC2_MOUSE	61	LRRA.\|.AVPR	inferred from experiment	unknown	MEROPS	Fricker LD	Pan H et al.:The role of prohormone converta... (S08.073)	16903874,
NEC2_MOUSE	65	VPRG.\|.GEAA	inferred from experiment	unknown	MEROPS	Fricker LD	Pan H et al.:The role of prohormone converta... (S08.073)	16903874,
NEC2_MOUSE	90	QERA.\|.ARAE	inferred from experiment	unknown	MEROPS	Fricker LD	Pan H et al.:The role of prohormone converta... (S08.073)	16903874,
CBPA4_MOUSE	237	GALL.\|.LRVK	inferred from experiment	unknown	MEROPS	Fricker LD	Tanco S et al.:Characterization of the substra... (M14.017)	20385563,
CBPA6_MOUSE	239	LLRV.\|.VKRL	inferred from experiment	unknown	MEROPS	Fricker LD	Lyons PJ et al.:Substrate specificity of human ... (M14.018)	20855895,
CBPA4_MOUSE	239	LLRV.\|.VKRL	inferred from experiment	unknown	MEROPS	Fricker LD	Tanco S et al.:Characterization of the substra... (M14.017)	20385563,
NEC2_MOUSE	242	VKRL.\|.LENP	inferred from experiment	unknown	MEROPS	Fricker LD	Pan H et al.:The role of prohormone converta... (S08.073)	16903874,

TopFIND

Q9QXV0: ProSAAS

General Information

9

N-termini

9

C-termini

11

Cleavages

0

Substrates

Sequence

Isoforms

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Domains & Features

9 N-termini - 9 C-termini - 11 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates