TopFIND 4.0

Q9R001: A disintegrin and metalloproteinase with thrombospondin motifs 5

General Information

Protein names
- A disintegrin and metalloproteinase with thrombospondin motifs 5
- ADAM-TS 5
- ADAM-TS5
- ADAMTS-5
- 3.4.24.-
- ADMP-2
- Aggrecanase-2
- Implantin
Gene names Adamts5
Organism Mus musculus
Protease Family
Protease ID M12.225
Chromosome location
UniProt ID Q9R001

4

N-termini

4

C-termini

3

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRLEWAPLLL LLLLLSASCL SLAADSPAAA PAQDKTRQPQ AAAAAAEPDQ PQGEETRERG 
        70         80         90        100        110        120 
HLQPLAGQRR SGGLVQNIDQ LYSGGGKVGY LVYAGGRRFL LDLERDDTVG AAGSIVTAGG 
       130        140        150        160        170        180 
GLSASSGHRG HCFYRGTVDG SPRSLAVFDL CGGLDGFFAV KHARYTLKPL LRGSWAEYER 
       190        200        210        220        230        240 
IYGDGSSRIL HVYNREGFSF EALPPRASCE TPASPSGPQE SPSVHSRSRR RSALAPQLLD 
       250        260        270        280        290        300 
HSAFSPSGNA GPQTWWRRRR RSISRARQVE LLLVADSSMA RMYGRGLQHY LLTLASIANR 
       310        320        330        340        350        360 
LYSHASIENH IRLAVVKVVV LTDKDTSLEV SKNAATTLKN FCKWQHQHNQ LGDDHEEHYD 
       370        380        390        400        410        420 
AAILFTREDL CGHHSCDTLG MADVGTICSP ERSCAVIEDD GLHAAFTVAH EIGHLLGLSH 
       430        440        450        460        470        480 
DDSKFCEENF GTTEDKRLMS SILTSIDASK PWSKCTSATI TEFLDDGHGN CLLDLPRKQI 
       490        500        510        520        530        540 
LGPEELPGQT YDATQQCNLT FGPEYSVCPG MDVCARLWCA VVRQGQMVCL TKKLPAVEGT 
       550        560        570        580        590        600 
PCGKGRVCLQ GKCVDKTKKK YYSTSSHGNW GSWGPWGQCS RSCGGGVQFA YRHCNNPAPR 
       610        620        630        640        650        660 
NSGRYCTGKR AIYRSCSVTP CPPNGKSFRH EQCEAKNGYQ SDAKGVKTFV EWVPKYAGVL 
       670        680        690        700        710        720 
PADVCKLTCR AKGTGYYVVF SPKVTDGTEC RPYSNSVCVR GRCVRTGCDG IIGSKLQYDK 
       730        740        750        760        770        780 
CGVCGGDNSS CTKIIGTFNK KSKGYTDVVR IPEGATHIKV RQFKAKDQTR FTAYLALKKK 
       790        800        810        820        830        840 
TGEYLINGKY MISTSETIID INGTVMNYSG WSHRDDFLHG MGYSATKEIL IVQILATDPT 
       850        860        870        880        890        900 
KALDVRYSFF VPKKTTQKVN SVISHGSNKV GPHSTQLQWV TGPWLACSRT CDTGWHTRTV 
       910        920        930    
QCQDGNRKLA KGCLLSQRPS AFKQCLLKKC 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)