Q9R0E2: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

General Information

Protein names	- Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 - 1.14.11.4 {ECO:0000250\|UniProtKB:P24802} - Lysyl hydroxylase 1 - LH1
Gene names	Plod1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9R0E2

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRSLLLLAPL AWLLLVQAKD DAKLEDNLLV LTVATKETEG FRRFKRSAQF FNYKIQSLGL
        70         80         90        100        110        120
GEDWSVDGGP AAAGGGQKVR LLKKALEKHA DKEDLVILFV DSYDVVFASG PRELLKKFQQ
       130        140        150        160        170        180
AKSQVVFSAE EHIYPDRRLE AKYPTVPDGK RFLGSGGFIG YAPSLSKLVA EWEGQDSDSD
       190        200        210        220        230        240
QLFYTKIFLN PEKREQINIS LDHRCRIFQN LDGALDEVVL KFEMGHVRAR NLAYDTLPVV
       250        260        270        280        290        300
VHGNGPTKLQ LNYLGNYIPR FWTFETGCTV CDEGLRSLKG IGDEALPTVL VGVFIEQPTP
       310        320        330        340        350        360
FLSLFFLRLL RLRYPQKQMR LFIHNQERHH KLQVEQFLAE HGSEYQSVKL VGPEVRMANA
       370        380        390        400        410        420
DARNMGADLC RQDQTCTYYF SVDADVALTE PNSLRLLIEQ NKNVIAPLMT RHGRLWSNFW
       430        440        450        460        470        480
GGLSADGYYA RSEDYVDIVQ GRRVGVWNVP YISNIYLIKG SALRAELQNV DLFHYSKLDS
       490        500        510        520        530        540
DMSFCANVRQ QEVFMFLTNR HTFGHLLSLD NYQTTHLHND LWEVFSNPED WKEKYIHENY
       550        560        570        580        590        600
TKALAGKLVE TPCPDVYWFP IFTEAACDEL VEEMEHYGQW SLGDNKDNRI QGGYENVPTI
       610        620        630        640        650        660
DIHMNQITFE REWHKFLVEY IAPMTEKLYP GYYTRAQFDL AFVVRYKPDE QPSLMPHHDA
       670        680        690        700        710        720
STFTVNIALN RVGEDYEGGG CRFLRYNCSV RAPRKGWALL HPGRLTHYHE GLPTTKGTRY

IAVSFVDP

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9R0E2-19-unknown	KDDAKL...	19	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9R0E2-19-unknown	KDDAKL...	19	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9R0E2-19-unmodified	KDDAKL...	19		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q9R0E2-423-unknown	LSADGY...	423	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34382

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NFWGGL	422	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34382
...GYYTRA	635	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118857
...SFVDP	728	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	422	WGGL.\|.LSAD	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)