Q9UBQ7: Glyoxylate reductase/hydroxypyruvate reductase

General Information

Protein names	- Glyoxylate reductase/hydroxypyruvate reductase - 1.1.1.79 - 1.1.1.81
Gene names	GRHPR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UBQ7

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRPVRLMKVF VTRRIPAEGR VALARAADCE VEQWDSDEPI PAKELERGVA GAHGLLCLLS
        70         80         90        100        110        120
DHVDKRILDA AGANLKVIST MSVGIDHLAL DEIKKRGIRV GYTPDVLTDT TAELAVSLLL
       130        140        150        160        170        180
TTCRRLPEAI EEVKNGGWTS WKPLWLCGYG LTQSTVGIIG LGRIGQAIAR RLKPFGVQRF
       190        200        210        220        230        240
LYTGRQPRPE EAAEFQAEFV STPELAAQSD FIVVACSLTP ATEGLCNKDF FQKMKETAVF
       250        260        270        280        290        300
INISRGDVVN QDDLYQALAS GKIAAAGLDV TSPEPLPTNH PLLTLKNCVI LPHIGSATHR
       310        320
TRNTMSLLAA NNLLAGLRGE PMPSELKL

Isoforms

- Isoform 2 of Glyoxylate reductase/hydroxypyruvate reductase

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9UBQ7-1-unknown	MRPVRL...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UBQ7-7-unknown	MKVFVT...	7	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q9UBQ7-85-unknown	IDHLAL...	85	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6833

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...TMSVGI	84	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6833
...SELKL	328	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...SELKL	328		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...SELKL	328		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...SELKL	328		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...SELKL	328		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	84	SVGI.\|.IDHL	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)