Q9UBW5: Bridging integrator 2

General Information

Protein names	- Bridging integrator 2 - Breast cancer-associated protein 1
Gene names	BIN2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UBW5

7 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Bridging integrator 2 - Isoform 3 of Bridging integrator 2

Sequence View

        10         20         30         40         50         60
MAEGKAGGAA GLFAKQVQKK FSRAQEKVLQ KLGKAVETKD ERFEQSASNF YQQQAEGHKL
        70         80         90        100        110        120
YKDLKNFLSA VKVMHESSKR VSETLQEIYS SEWDGHEELK AIVWNNDLLW EDYEEKLADQ
       130        140        150        160        170        180
AVRTMEIYVA QFSEIKERIA KRGRKLVDYD SARHHLEAVQ NAKKKDEAKT AKAEEEFNKA
       190        200        210        220        230        240
QTVFEDLNQE LLEELPILYN SRIGCYVTIF QNISNLRDVF YREMSKLNHN LYEVMSKLEK
       250        260        270        280        290        300
QHSNKVFVVK GLSSSSRRSL VISPPVRTAT VSSPLTSPTS PSTLSLKSES ESVSATEDLA
       310        320        330        340        350        360
PDAAQGEDNS EIKELLEEEE IEKEGSEASS SEEDEPLPAC NGPAQAQPSP TTERAKSQEE
       370        380        390        400        410        420
VLPSSTTPSP GGALSPSGQP SSSATEVVLR TRTASEGSEQ PKKRASIQRT SAPPSRPPPP
       430        440        450        460        470        480
RATASPRPSS GNIPSSPTAS GGGSPTSPRA SLGTGTASPR TSLEVSPNPE PPEKPVRTPE
       490        500        510        520        530        540
AKENENIHNQ NPEELCTSPT LMTSQVASEP GEAKKMEDKE KDNKLISANS SEGQDQLQVS
       550        560
MVPENNNLTA PEPQEEVSTS ENPQL         10         20         30         40         50         60
MAEGKAGGAA GLFAKQVQKK FSRAQEKVLQ KLGKAVETKD ERFEQSASNF YQQQAEGHKL
        70         80         90        100        110        120
YKDLKNFLSA VKVMHESSKR VSETLQEIYS SEWDGHEELK AIVWNNDLLW EDYEEKLADQ
       130        140        150        160        170        180
AVRTMEIYVA QFSEIKERIA KRGRKLVDYD SARHHLEAVQ NAKKKDEAKT AKAEEEFNKA
       190        200        210        220        230        240
QTVFEDLNQE LLEELPILYN SRIGCYVTIF QNISNLRDVF YREMSKLNHN LYEVMSKLEK
       250        260        270        280        290        300
QHSNKVFVVK GLSSSSRRSL VISPPVRTAT VSSPLTSPTS PSTLSLKSES ESVSATEDLA
       310        320        330        340        350        360
PDAAQGEDNS EIKELLEEEE IEKEGSEASS SEEDEPLPAC NGPAQAQPSP TTERAKSQEE
       370        380        390        400        410        420
VLPSSTTPSP GGALSPSGQP SSSATEVVLR TRTASEGSEQ PKKRASIQRT SAPPSRPPPP
       430        440        450        460        470        480
RATASPRPSS GNIPSSPTAS GGGSPTSPRA SLGTGTASPR TSLEVSPNPE PPEKPVRTPE
       490        500        510        520        530        540
AKENENIHNQ NPEELCTSPT LMTSQVASEP GEAKKMEDKE KDNKLISANS SEGQDQLQVS
       550        560
MVPENNNLTA PEPQEEVSTS ENPQL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UBW5-1-unknown	MAEGKA...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UBW5-1-unknown	MAEGKA...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt68476
Q9UBW5-346-unknown	AQPSPT...	346		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
Q9UBW5-346-unknown	AQPSPT...	346	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180195
Q9UBW5-462-unknown	SLEVSP...	462	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176292
Q9UBW5-462-	SLEVSP...	462		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UBW5-465-unknown	VSPNPE...	465		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
Q9UBW5-465-unknown	VSPNPE...	465	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180197
Q9UBW5-541-	MVPENN...	541		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9UBW5-541-unknown	MVPENN...	541	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176927

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...ENPQL	565	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...ENPQL	565	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt64094

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)