Q9UHJ3: Scm-like with four MBT domains protein 1

General Information

Protein names	- Scm-like with four MBT domains protein 1 - hSFMBT - Renal ubiquitous protein 1
Gene names	SFMBT1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UHJ3

4 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNGEQQLDAD AGSGMEEVEL SWEDYLEETG STAVPYGSFK HVDTRLQNGF APGMKLEVAV
        70         80         90        100        110        120
RTDPETYWVA TVITTCEQLL LLRYDGYGED RRADFWCDIR KADLYPIGWC EQNKKTLEAP
       130        140        150        160        170        180
EGIRDKVSDW DEFLRQTLIG ACSPPVPLLE GLRNGRNPLD LIAPGSRLEC QAFQDSLSTW
       190        200        210        220        230        240
IVTVVENIGG RLKLRYEGLE SSDNYEHWLY YLDPFLHHVG WAAQQGYELQ PPSAIRHLKN
       250        260        270        280        290        300
EAEWQEILAK VKEEEEEPLP SYLFKDKQVI GIHTFSVNMK LEAVDPWSPF GISPATVVKV
       310        320        330        340        350        360
FDEKYFLVEM DDLRPENHAR RSFVCHADSP GIFPVQWSLK NGLHISPPPG YPSQDFDWAD
       370        380        390        400        410        420
YLKQCGAEAA PQRCFPPLIS EHEFKENMKL EAVNPILPEE VCVATITAVR GSYLWLQLEG
       430        440        450        460        470        480
SKKPIPECIV SVESMDIFPL GWCETNGHPL STPRRARVYK QRKIAVVQPE KQVPSSRTVH
       490        500        510        520        530        540
EGLRNQELNS TESVMINGKY CCPKIYFNHR CFSGPYLNKG RIAELPQCVG PGNCVLVLRE
       550        560        570        580        590        600
VLTLLINAAY KPSRVLRELQ LDKDSVWHGC GEVLKAKYKG KSYRATVEIV KTADRVTEFC
       610        620        630        640        650        660
RQTCIKLECC PNLFGPRMVL DKCSENCSVL TKTKYTHYYG KKKNKRIGRP PGGHSNLACA
       670        680        690        700        710        720
LKKASKRRKR RKNVFVHKKK RSSASVDNTP AGSPQGSGGE DEDDPDEGDD DSLSEGSTSE
       730        740        750        760        770        780
QQDELQEESE MSEKKSCSSS PTQSEISTSL PPDRQRRKRE LRTFSFSDDE NKPPSPKEIR
       790        800        810        820        830        840
IEVAERLHLD SNPLKWSVAD VVRFIRSTDC APLARIFLDQ EIDGQALLLL TLPTVQECMD
       850        860
LKLGPAIKLC HHIERIKFAF YEQFAN

Isoforms

- Isoform 2 of Scm-like with four MBT domains protein 1

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9UHJ3-1-unknown	MNGEQQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UHJ3-1-unknown	MNGEQQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt90000
Q9UHJ3-33-unknown	AVPYGS...	33	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9580
Q9UHJ3-33-unknown	AVPYGS...	33	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137792
Q9UHJ3-34-unknown	VPYGSF...	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9582
Q9UHJ3-34-unknown	VPYGSF...	34	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137879
Q9UHJ3-36-unknown	YGSFKH...	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8512
Q9UHJ3-36-unknown	YGSFKH...	36	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt138009

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ETGSTA	32	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9580
...ETGSTA	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120793
...TGSTAV	33	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9582
...TGSTAV	33	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120886
...STAVPY	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8512
...STAVPY	35	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121023
...EQFAN	866	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EQFAN	866	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85618

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
ERAP2_HUMAN	32	GSTA.\|.AVPY	inferred from experiment	unknown	MEROPS	Tsujimoto M	Tanioka T et al.:Human leukocyte-derived arginin... (M01.024)	12799365,
ERAP2_HUMAN	33	STAV.\|.VPYG	inferred from experiment	unknown	MEROPS	Tsujimoto M	Tanioka T et al.:Human leukocyte-derived arginin... (M01.024)	12799365,
DPP9_HUMAN	35	AVPY.\|.YGSF	inferred from experiment	unknown	MEROPS	Melchior F	Geiss-Friedlander R et al.:The cytoplasmic peptidase DPP9 ... (S09.019)	19667070,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)