Q9UHQ1: Nuclear prelamin A recognition factor

General Information

Protein names	- Nuclear prelamin A recognition factor - Iron-only hydrogenase-like protein 2 - IOP2
Gene names	NARF
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UHQ1

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Nuclear prelamin A recognition factor - Isoform 3 of Nuclear prelamin A recognition factor - Isoform 4 of Nuclear prelamin A recognition factor

Sequence View

        10         20         30         40         50         60
MKCEHCTRKE CSKKTKTDDQ ENVSADAPSP AQENGEKGEF HKLADAKIFL SDCLACDSCM
        70         80         90        100        110        120
TAEEGVQLSQ QNAKDFFRVL NLNKKCDTSK HKVLVVSVCP QSLPYFAAKF NLSVTDASRR
       130        140        150        160        170        180
LCGFLKSLGV HYVFDTTIAA DFSILESQKE FVRRYRQHSE EERTLPMLTS ACPGWVRYAE
       190        200        210        220        230        240
RVLGRPITAH LCTAKSPQQV MGSLVKDYFA RQQNLSPEKI FHVIVAPCYD KKLEALQESL
       250        260        270        280        290        300
PPALHGSRGA DCVLTSGEIA QIMEQGDLSV RDAAVDTLFG DLKEDKVTRH DGASSDGHLA
       310        320        330        340        350        360
HIFRHAAKEL FNEDVEEVTY RALRNKDFQE VTLEKNGEVV LRFAAAYGFR NIQNMILKLK
       370        380        390        400        410        420
KGKFPFHFVE VLACAGGCLN GRGQAQTPDG HADKALLRQM EGIYADIPVR RPESSAHVQE
       430        440        450
LYQEWLEGIN SPKAREVLHT TYQSQERGTH SLDIKW         10         20         30         40         50         60
MKCEHCTRKE CSKKTKTDDQ ENVSADAPSP AQENGEKGEF HKLADAKIFL SDCLACDSCM
        70         80         90        100        110        120
TAEEGVQLSQ QNAKDFFRVL NLNKKCDTSK HKVLVVSVCP QSLPYFAAKF NLSVTDASRR
       130        140        150        160        170        180
LCGFLKSLGV HYVFDTTIAA DFSILESQKE FVRRYRQHSE EERTLPMLTS ACPGWVRYAE
       190        200        210        220        230        240
RVLGRPITAH LCTAKSPQQV MGSLVKDYFA RQQNLSPEKI FHVIVAPCYD KKLEALQESL
       250        260        270        280        290        300
PPALHGSRGA DCVLTSGEIA QIMEQGDLSV RDAAVDTLFG DLKEDKVTRH DGASSDGHLA
       310        320        330        340        350        360
HIFRHAAKEL FNEDVEEVTY RALRNKDFQE VTLEKNGEVV LRFAAAYGFR NIQNMILKLK
       370        380        390        400        410        420
KGKFPFHFVE VLACAGGCLN GRGQAQTPDG HADKALLRQM EGIYADIPVR RPESSAHVQE
       430        440        450
LYQEWLEGIN SPKAREVLHT TYQSQERGTH SLDIKW         10         20         30         40         50         60
MKCEHCTRKE CSKKTKTDDQ ENVSADAPSP AQENGEKGEF HKLADAKIFL SDCLACDSCM
        70         80         90        100        110        120
TAEEGVQLSQ QNAKDFFRVL NLNKKCDTSK HKVLVVSVCP QSLPYFAAKF NLSVTDASRR
       130        140        150        160        170        180
LCGFLKSLGV HYVFDTTIAA DFSILESQKE FVRRYRQHSE EERTLPMLTS ACPGWVRYAE
       190        200        210        220        230        240
RVLGRPITAH LCTAKSPQQV MGSLVKDYFA RQQNLSPEKI FHVIVAPCYD KKLEALQESL
       250        260        270        280        290        300
PPALHGSRGA DCVLTSGEIA QIMEQGDLSV RDAAVDTLFG DLKEDKVTRH DGASSDGHLA
       310        320        330        340        350        360
HIFRHAAKEL FNEDVEEVTY RALRNKDFQE VTLEKNGEVV LRFAAAYGFR NIQNMILKLK
       370        380        390        400        410        420
KGKFPFHFVE VLACAGGCLN GRGQAQTPDG HADKALLRQM EGIYADIPVR RPESSAHVQE
       430        440        450
LYQEWLEGIN SPKAREVLHT TYQSQERGTH SLDIKW

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UHQ1-1-unknown	MKCEHC...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UHQ1-1-unknown	MKCEHC...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82289
Q9UHQ1-1-unknown	MKCEHC...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82290
Q9UHQ1-60-unknown	MTAEEG...	60	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82291
Q9UHQ1-60-unknown	MTAEEG...	60	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt102463
Q9UHQ1-273-unknown	AAVDTL...	273	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174155
Q9UHQ1-273-unknown	AAVDTL...	273	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174156
Q9UHQ1-273-unknown	AAVDTL...	273	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174157
Q9UHQ1-273-	AAVDTL...	273		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UHQ1-273-	AAVDTL...	273		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LDIKW	456	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LDIKW	456	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77909
...LDIKW	456	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77908
...LDIKW	456	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77907

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)