Q9UK23: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

General Information

Protein names	- N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase - 3.1.4.45 - Mannose 6-phosphate-uncovering enzyme - Phosphodiester alpha-GlcNAcase
Gene names	NAGPA
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UK23

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase - Isoform 3 of N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

Sequence View

        10         20         30         40         50         60
MATSTGRWLL LRLALFGFLW EASGGLDSGA SRDDDLLLPY PRARARLPRD CTRVRAGNRE
        70         80         90        100        110        120
HESWPPPPAT PGAGGLAVRT FVSHFRDRAV AGHLTRAVEP LRTFSVLEPG GPGGCAARRR
       130        140        150        160        170        180
ATVEETARAA DCRVAQNGGF FRMNSGECLG NVVSDERRVS SSGGLQNAQF GIRRDGTLVT
       190        200        210        220        230        240
GYLSEEEVLD TENPFVQLLS GVVWLIRNGS IYINESQATE CDETQETGSF SKFVNVISAR
       250        260        270        280        290        300
TAIGHDRKGQ LVLFHADGQT EQRGINLWEM AEFLLKQDVV NAINLDGGGS ATFVLNGTLA
       310        320        330        340        350        360
SYPSDHCQDN MWRCPRQVST VVCVHEPRCQ PPDCHGHGTC VDGHCQCTGH FWRGPGCDEL
       370        380        390        400        410        420
DCGPSNCSQH GLCTETGCRC DAGWTGSNCS EECPLGWHGP GCQRPCKCEH HCPCDPKTGN
       430        440        450        460        470        480
CSVSRVKQCL QPPEATLRAG ELSFFTRTAW LALTLALAFL LLISTAANLS LLLSRAERNR
       490        500        510
RLHGDYAYHP LQEMNGEPLA AEKEQPGGAH NPFKD         10         20         30         40         50         60
MATSTGRWLL LRLALFGFLW EASGGLDSGA SRDDDLLLPY PRARARLPRD CTRVRAGNRE
        70         80         90        100        110        120
HESWPPPPAT PGAGGLAVRT FVSHFRDRAV AGHLTRAVEP LRTFSVLEPG GPGGCAARRR
       130        140        150        160        170        180
ATVEETARAA DCRVAQNGGF FRMNSGECLG NVVSDERRVS SSGGLQNAQF GIRRDGTLVT
       190        200        210        220        230        240
GYLSEEEVLD TENPFVQLLS GVVWLIRNGS IYINESQATE CDETQETGSF SKFVNVISAR
       250        260        270        280        290        300
TAIGHDRKGQ LVLFHADGQT EQRGINLWEM AEFLLKQDVV NAINLDGGGS ATFVLNGTLA
       310        320        330        340        350        360
SYPSDHCQDN MWRCPRQVST VVCVHEPRCQ PPDCHGHGTC VDGHCQCTGH FWRGPGCDEL
       370        380        390        400        410        420
DCGPSNCSQH GLCTETGCRC DAGWTGSNCS EECPLGWHGP GCQRPCKCEH HCPCDPKTGN
       430        440        450        460        470        480
CSVSRVKQCL QPPEATLRAG ELSFFTRTAW LALTLALAFL LLISTAANLS LLLSRAERNR
       490        500        510
RLHGDYAYHP LQEMNGEPLA AEKEQPGGAH NPFKD

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UK23-1-unknown	MATSTG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82210
Q9UK23-1-unknown	MATSTG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82211
Q9UK23-25-unknown	GLDSGA...	25	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171420
Q9UK23-25-unknown	GLDSGA...	25	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171421
Q9UK23-25-	GLDSGA...	25		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UK23-50-unknown	DCTRVR...	50	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UK23-50-unknown	DCTRVR...	50	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115634
Q9UK23-50-unknown	DCTRVR...	50	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115635

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...NPFKD	515	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...NPFKD	515	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt77828

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)