Q9UKA9: Polypyrimidine tract-binding protein 2

General Information

Protein names	- Polypyrimidine tract-binding protein 2 - Neural polypyrimidine tract-binding protein - Neurally-enriched homolog of PTB - PTB-like protein
Gene names	PTBP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UKA9

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Polypyrimidine tract-binding protein 2 - Isoform 3 of Polypyrimidine tract-binding protein 2 - Isoform 4 of Polypyrimidine tract-binding protein 2 - Isoform 5 of Polypyrimidine tract-binding protein 2 - Isoform 6 of Polypyrimidine tract-binding protein 2

Sequence View

        10         20         30         40         50         60
MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSSMVVTAN GNDSKKFKGE DKMDGAPSRV
        70         80         90        100        110        120
LHIRKLPGEV TETEVIALGL PFGKVTNILM LKGKNQAFLE LATEEAAITM VNYYSAVTPH
       130        140        150        160        170        180
LRNQPIYIQY SNHKELKTDN TLNQRAQAVL QAVTAVQTAN TPLSGTTVSE SAVTPAQSPV
       190        200        210        220        230        240
LRIIIDNMYY PVTLDVLHQI FSKFGAVLKI ITFTKNNQFQ ALLQYGDPVN AQQAKLALDG
       250        260        270        280        290        300
QNIYNACCTL RIDFSKLVNL NVKYNNDKSR DYTRPDLPSG DGQPALDPAI AAAFAKETSL
       310        320        330        340        350        360
LAVPGALSPL AIPNAAAAAA AAAAGRVGMP GVSAGGNTVL LVSNLNEEMV TPQSLFTLFG
       370        380        390        400        410        420
VYGDVQRVKI LYNKKDSALI QMADGNQSQL AMNHLNGQKM YGKIIRVTLS KHQTVQLPRE
       430        440        450        460        470        480
GLDDQGLTKD FGNSPLHRFK KPGSKNFQNI FPPSATLHLS NIPPSVAEED LRTLFANTGG
       490        500        510        520        530
TVKAFKFFQD HKMALLQMAT VEEAIQALID LHNYNLGENH HLRVSFSKST I         10         20         30         40         50         60
MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSSMVVTAN GNDSKKFKGE DKMDGAPSRV
        70         80         90        100        110        120
LHIRKLPGEV TETEVIALGL PFGKVTNILM LKGKNQAFLE LATEEAAITM VNYYSAVTPH
       130        140        150        160        170        180
LRNQPIYIQY SNHKELKTDN TLNQRAQAVL QAVTAVQTAN TPLSGTTVSE SAVTPAQSPV
       190        200        210        220        230        240
LRIIIDNMYY PVTLDVLHQI FSKFGAVLKI ITFTKNNQFQ ALLQYGDPVN AQQAKLALDG
       250        260        270        280        290        300
QNIYNACCTL RIDFSKLVNL NVKYNNDKSR DYTRPDLPSG DGQPALDPAI AAAFAKETSL
       310        320        330        340        350        360
LAVPGALSPL AIPNAAAAAA AAAAGRVGMP GVSAGGNTVL LVSNLNEEMV TPQSLFTLFG
       370        380        390        400        410        420
VYGDVQRVKI LYNKKDSALI QMADGNQSQL AMNHLNGQKM YGKIIRVTLS KHQTVQLPRE
       430        440        450        460        470        480
GLDDQGLTKD FGNSPLHRFK KPGSKNFQNI FPPSATLHLS NIPPSVAEED LRTLFANTGG
       490        500        510        520        530
TVKAFKFFQD HKMALLQMAT VEEAIQALID LHNYNLGENH HLRVSFSKST I         10         20         30         40         50         60
MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSSMVVTAN GNDSKKFKGE DKMDGAPSRV
        70         80         90        100        110        120
LHIRKLPGEV TETEVIALGL PFGKVTNILM LKGKNQAFLE LATEEAAITM VNYYSAVTPH
       130        140        150        160        170        180
LRNQPIYIQY SNHKELKTDN TLNQRAQAVL QAVTAVQTAN TPLSGTTVSE SAVTPAQSPV
       190        200        210        220        230        240
LRIIIDNMYY PVTLDVLHQI FSKFGAVLKI ITFTKNNQFQ ALLQYGDPVN AQQAKLALDG
       250        260        270        280        290        300
QNIYNACCTL RIDFSKLVNL NVKYNNDKSR DYTRPDLPSG DGQPALDPAI AAAFAKETSL
       310        320        330        340        350        360
LAVPGALSPL AIPNAAAAAA AAAAGRVGMP GVSAGGNTVL LVSNLNEEMV TPQSLFTLFG
       370        380        390        400        410        420
VYGDVQRVKI LYNKKDSALI QMADGNQSQL AMNHLNGQKM YGKIIRVTLS KHQTVQLPRE
       430        440        450        460        470        480
GLDDQGLTKD FGNSPLHRFK KPGSKNFQNI FPPSATLHLS NIPPSVAEED LRTLFANTGG
       490        500        510        520        530
TVKAFKFFQD HKMALLQMAT VEEAIQALID LHNYNLGENH HLRVSFSKST I         10         20         30         40         50         60
MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSSMVVTAN GNDSKKFKGE DKMDGAPSRV
        70         80         90        100        110        120
LHIRKLPGEV TETEVIALGL PFGKVTNILM LKGKNQAFLE LATEEAAITM VNYYSAVTPH
       130        140        150        160        170        180
LRNQPIYIQY SNHKELKTDN TLNQRAQAVL QAVTAVQTAN TPLSGTTVSE SAVTPAQSPV
       190        200        210        220        230        240
LRIIIDNMYY PVTLDVLHQI FSKFGAVLKI ITFTKNNQFQ ALLQYGDPVN AQQAKLALDG
       250        260        270        280        290        300
QNIYNACCTL RIDFSKLVNL NVKYNNDKSR DYTRPDLPSG DGQPALDPAI AAAFAKETSL
       310        320        330        340        350        360
LAVPGALSPL AIPNAAAAAA AAAAGRVGMP GVSAGGNTVL LVSNLNEEMV TPQSLFTLFG
       370        380        390        400        410        420
VYGDVQRVKI LYNKKDSALI QMADGNQSQL AMNHLNGQKM YGKIIRVTLS KHQTVQLPRE
       430        440        450        460        470        480
GLDDQGLTKD FGNSPLHRFK KPGSKNFQNI FPPSATLHLS NIPPSVAEED LRTLFANTGG
       490        500        510        520        530
TVKAFKFFQD HKMALLQMAT VEEAIQALID LHNYNLGENH HLRVSFSKST I         10         20         30         40         50         60
MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSSMVVTAN GNDSKKFKGE DKMDGAPSRV
        70         80         90        100        110        120
LHIRKLPGEV TETEVIALGL PFGKVTNILM LKGKNQAFLE LATEEAAITM VNYYSAVTPH
       130        140        150        160        170        180
LRNQPIYIQY SNHKELKTDN TLNQRAQAVL QAVTAVQTAN TPLSGTTVSE SAVTPAQSPV
       190        200        210        220        230        240
LRIIIDNMYY PVTLDVLHQI FSKFGAVLKI ITFTKNNQFQ ALLQYGDPVN AQQAKLALDG
       250        260        270        280        290        300
QNIYNACCTL RIDFSKLVNL NVKYNNDKSR DYTRPDLPSG DGQPALDPAI AAAFAKETSL
       310        320        330        340        350        360
LAVPGALSPL AIPNAAAAAA AAAAGRVGMP GVSAGGNTVL LVSNLNEEMV TPQSLFTLFG
       370        380        390        400        410        420
VYGDVQRVKI LYNKKDSALI QMADGNQSQL AMNHLNGQKM YGKIIRVTLS KHQTVQLPRE
       430        440        450        460        470        480
GLDDQGLTKD FGNSPLHRFK KPGSKNFQNI FPPSATLHLS NIPPSVAEED LRTLFANTGG
       490        500        510        520        530
TVKAFKFFQD HKMALLQMAT VEEAIQALID LHNYNLGENH HLRVSFSKST I

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UKA9-1-unknown	MDGIVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86433
Q9UKA9-1-unknown	MDGIVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86434
Q9UKA9-1-unknown	MDGIVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86435
Q9UKA9-1-unknown	MDGIVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86436
Q9UKA9-1-unknown	MDGIVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86437
Q9UKA9-1-Acetylation	MDGIVT...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UKA9-1-Acetylation	MDGIVT...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108710
Q9UKA9-1-Acetylation	MDGIVT...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108711
Q9UKA9-1-Acetylation	MDGIVT...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108712
Q9UKA9-1-Acetylation	MDGIVT...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108713
Q9UKA9-1-Acetylation	MDGIVT...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108714
Q9UKA9-293-	AFAKET...	293			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UKA9-293-unknown	AFAKET...	293		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171900
Q9UKA9-293-unknown	AFAKET...	293		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171901

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SKSTI	531	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SKSTI	531	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82051
...SKSTI	531	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82053
...SKSTI	531	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82052

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)