Q9UKV5: E3 ubiquitin-protein ligase AMFR

General Information

Protein names	- E3 ubiquitin-protein ligase AMFR - 2.3.2.27 {ECO:0000269\|PubMed:11724934, ECO:0000269\|PubMed:16168377} - Autocrine motility factor receptor - AMF receptor - RING finger protein 45 - RING-type E3 ubiquitin transferase AMFR {ECO:0000305} - gp78
Gene names	AMFR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UKV5

4 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPLLFLERFP WPSLRTYTGL SGLALLGTII SAYRALSQPE AGPGEPDQLT ASLQPEPPAP
        70         80         90        100        110        120
ARPSAGGPRA RDVAQYLLSD SLFVWVLVNT ACCVLMLVAK LIQCIVFGPL RVSERQHLKD
       130        140        150        160        170        180
KFWNFIFYKF IFIFGVLNVQ TVEEVVMWCL WFAGLVFLHL MVQLCKDRFE YLSFSPTTPM
       190        200        210        220        230        240
SSHGRVLSLL VAMLLSCCGL AAVCSITGYT HGMHTLAFMA AESLLVTVRT AHVILRYVIH
       250        260        270        280        290        300
LWDLNHEGTW EGKGTYVYYT DFVMELTLLS LDLMHHIHML LFGNIWLSMA SLVIFMQLRY
       310        320        330        340        350        360
LFHEVQRRIR RHKNYLRVVG NMEARFAVAT PEELAVNNDD CAICWDSMQA ARKLPCGHLF
       370        380        390        400        410        420
HNSCLRSWLE QDTSCPTCRM SLNIADNNRV REEHQGENLD ENLVPVAAAE GRPRLNQHNH
       430        440        450        460        470        480
FFHFDGSRIA SWLPSFSVEV MHTTNILGIT QASNSQLNAM AHQIQEMFPQ VPYHLVLQDL
       490        500        510        520        530        540
QLTRSVEITT DNILEGRIQV PFPTQRSDSI RPALNSPVER PSSDQEEGET SAQTERVPLD
       550        560        570        580        590        600
LSPRLEETLD FGEVEVEPSE VEDFEARGSR FSKSADERQR MLVQRKDELL QQARKRFLNK
       610        620        630        640
SSEDDAASES FLPSEGASSD PVTLRRRMLA AAAERRLQKQ QTS

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UKV5-1-unknown	MPLLFL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UKV5-96-unknown	MLVAKL...	96	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000456745
Q9UKV5-96-unknown	MLVAKL...	96	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000455842
Q9UKV5-286-unknown	WLSMAS...	286	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000456288
Q9UKV5-554-	VEVEPS...	554		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YVYYTD	260	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455842
...GNMEAR	324	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456745
...VPLDLS	541	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456288
...KQQTS	643	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)