Q9UMX0: Ubiquilin-1

General Information

Protein names	- Ubiquilin-1 - Protein linking IAP with cytoskeleton 1 - PLIC-1 - hPLIC-1
Gene names	UBQLN1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UMX0

7 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Ubiquilin-1 - Isoform 3 of Ubiquilin-1 - Isoform 4 of Ubiquilin-1

Sequence View

        10         20         30         40         50         60
MAESGESGGP PGSQDSAAGA EGAGAPAAAA SAEPKIMKVT VKTPKEKEEF AVPENSSVQQ
        70         80         90        100        110        120
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT
       130        140        150        160        170        180
NTAGSNVTTS STPNSNSTSG SATSNPFGLG GLGGLAGLSS LGLNTTNFSE LQSQMQRQLL
       190        200        210        220        230        240
SNPEMMVQIM ENPFVQSMLS NPDLMRQLIM ANPQMQQLIQ RNPEISHMLN NPDIMRQTLE
       250        260        270        280        290        300
LARNPAMMQE MMRNQDRALS NLESIPGGYN ALRRMYTDIQ EPMLSAAQEQ FGGNPFASLV
       310        320        330        340        350        360
SNTSSGEGSQ PSRTENRDPL PNPWAPQTSQ SSSASSGTAS TVGGTTGSTA SGTSGQSTTA
       370        380        390        400        410        420
PNLVPGVGAS MFNTPGMQSL LQQITENPQL MQNMLSAPYM RSMMQSLSQN PDLAAQMMLN
       430        440        450        460        470        480
NPLFAGNPQL QEQMRQQLPT FLQQMQNPDT LSAMSNPRAM QALLQIQQGL QTLATEAPGL
       490        500        510        520        530        540
IPGFTPGLGA LGSTGGSSGT NGSNATPSEN TSPTAGTTEP GHQQFIQQML QALAGVNPQL
       550        560        570        580
QNPEVRFQQQ LEQLSAMGFL NREANLQALI ATGGDINAAI ERLLGSQPS         10         20         30         40         50         60
MAESGESGGP PGSQDSAAGA EGAGAPAAAA SAEPKIMKVT VKTPKEKEEF AVPENSSVQQ
        70         80         90        100        110        120
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT
       130        140        150        160        170        180
NTAGSNVTTS STPNSNSTSG SATSNPFGLG GLGGLAGLSS LGLNTTNFSE LQSQMQRQLL
       190        200        210        220        230        240
SNPEMMVQIM ENPFVQSMLS NPDLMRQLIM ANPQMQQLIQ RNPEISHMLN NPDIMRQTLE
       250        260        270        280        290        300
LARNPAMMQE MMRNQDRALS NLESIPGGYN ALRRMYTDIQ EPMLSAAQEQ FGGNPFASLV
       310        320        330        340        350        360
SNTSSGEGSQ PSRTENRDPL PNPWAPQTSQ SSSASSGTAS TVGGTTGSTA SGTSGQSTTA
       370        380        390        400        410        420
PNLVPGVGAS MFNTPGMQSL LQQITENPQL MQNMLSAPYM RSMMQSLSQN PDLAAQMMLN
       430        440        450        460        470        480
NPLFAGNPQL QEQMRQQLPT FLQQMQNPDT LSAMSNPRAM QALLQIQQGL QTLATEAPGL
       490        500        510        520        530        540
IPGFTPGLGA LGSTGGSSGT NGSNATPSEN TSPTAGTTEP GHQQFIQQML QALAGVNPQL
       550        560        570        580
QNPEVRFQQQ LEQLSAMGFL NREANLQALI ATGGDINAAI ERLLGSQPS         10         20         30         40         50         60
MAESGESGGP PGSQDSAAGA EGAGAPAAAA SAEPKIMKVT VKTPKEKEEF AVPENSSVQQ
        70         80         90        100        110        120
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT
       130        140        150        160        170        180
NTAGSNVTTS STPNSNSTSG SATSNPFGLG GLGGLAGLSS LGLNTTNFSE LQSQMQRQLL
       190        200        210        220        230        240
SNPEMMVQIM ENPFVQSMLS NPDLMRQLIM ANPQMQQLIQ RNPEISHMLN NPDIMRQTLE
       250        260        270        280        290        300
LARNPAMMQE MMRNQDRALS NLESIPGGYN ALRRMYTDIQ EPMLSAAQEQ FGGNPFASLV
       310        320        330        340        350        360
SNTSSGEGSQ PSRTENRDPL PNPWAPQTSQ SSSASSGTAS TVGGTTGSTA SGTSGQSTTA
       370        380        390        400        410        420
PNLVPGVGAS MFNTPGMQSL LQQITENPQL MQNMLSAPYM RSMMQSLSQN PDLAAQMMLN
       430        440        450        460        470        480
NPLFAGNPQL QEQMRQQLPT FLQQMQNPDT LSAMSNPRAM QALLQIQQGL QTLATEAPGL
       490        500        510        520        530        540
IPGFTPGLGA LGSTGGSSGT NGSNATPSEN TSPTAGTTEP GHQQFIQQML QALAGVNPQL
       550        560        570        580
QNPEVRFQQQ LEQLSAMGFL NREANLQALI ATGGDINAAI ERLLGSQPS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UMX0-2-unknown	MAESGE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UMX0-1-unknown	MAESGE...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93746
Q9UMX0-2-Acetylation	AESGES...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UMX0-2-Acetylation	AESGES...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9UMX0-2-Acetylation	AESGES...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110647
Q9UMX0-16-	SAAGAE...	16			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UMX0-16-	SAAGAE...	16			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UMX0-16-unknown	SAAGAE...	16		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172432
Q9UMX0-292-unknown	GGNPFA...	292		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175323
Q9UMX0-292-	GGNPFA...	292			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GSQPS	589	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...GSQPS	589	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt89364

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)