Q9UMX1: Suppressor of fused homolog {ECO:0000303|PubMed:10559945, ECO:0000303|PubMed:10564661}

General Information

Protein names	- Suppressor of fused homolog {ECO:0000303\|PubMed:10559945, ECO:0000303\|PubMed:10564661} - SUFUH {ECO:0000303\|PubMed:10559945}
Gene names	SUFU
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UMX1

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Suppressor of fused homolog - Isoform 3 of Suppressor of fused homolog

Sequence View

        10         20         30         40         50         60
MAELRPSGAP GPTAPPAPGP TAPPAFASLF PPGLHAIYGE CRRLYPDQPN PLQVTAIVKY
        70         80         90        100        110        120
WLGGPDPLDY VSMYRNVGSP SANIPEHWHY ISFGLSDLYG DNRVHEFTGT DGPSGFGFEL
       130        140        150        160        170        180
TFRLKRETGE SAPPTWPAEL MQGLARYVFQ SENTFCSGDH VSWHSPLDNS ESRIQHMLLT
       190        200        210        220        230        240
EDPQMQPVQT PFGVVTFLQI VGVCTEELHS AQQWNGQGIL ELLRTVPIAG GPWLITDMRR
       250        260        270        280        290        300
GETIFEIDPH LQERVDKGIE TDGSNLSGVS AKCAWDDLSR PPEDDEDSRS ICIGTQPRRL
       310        320        330        340        350        360
SGKDTEQIRE TLRRGLEINS KPVLPPINPQ RQNGLAHDRA PSRKDSLESD SSTAIIPHEL
       370        380        390        400        410        420
IRTRQLESVH LKFNQESGAL IPLCLRGRLL HGRHFTYKSI TGDMAITFVS TGVEGAFATE
       430        440        450        460        470        480
EHPYAAHGPW LQILLTEEFV EKMLEDLEDL TSPEEFKLPK EYSWPEKKLK VSILPDVVFD

SPLH         10         20         30         40         50         60
MAELRPSGAP GPTAPPAPGP TAPPAFASLF PPGLHAIYGE CRRLYPDQPN PLQVTAIVKY
        70         80         90        100        110        120
WLGGPDPLDY VSMYRNVGSP SANIPEHWHY ISFGLSDLYG DNRVHEFTGT DGPSGFGFEL
       130        140        150        160        170        180
TFRLKRETGE SAPPTWPAEL MQGLARYVFQ SENTFCSGDH VSWHSPLDNS ESRIQHMLLT
       190        200        210        220        230        240
EDPQMQPVQT PFGVVTFLQI VGVCTEELHS AQQWNGQGIL ELLRTVPIAG GPWLITDMRR
       250        260        270        280        290        300
GETIFEIDPH LQERVDKGIE TDGSNLSGVS AKCAWDDLSR PPEDDEDSRS ICIGTQPRRL
       310        320        330        340        350        360
SGKDTEQIRE TLRRGLEINS KPVLPPINPQ RQNGLAHDRA PSRKDSLESD SSTAIIPHEL
       370        380        390        400        410        420
IRTRQLESVH LKFNQESGAL IPLCLRGRLL HGRHFTYKSI TGDMAITFVS TGVEGAFATE
       430        440        450        460        470        480
EHPYAAHGPW LQILLTEEFV EKMLEDLEDL TSPEEFKLPK EYSWPEKKLK VSILPDVVFD

SPLH

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UMX1-1-unknown	MAELRP...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UMX1-1-unknown	MAELRP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt91049
Q9UMX1-1-unknown	MAELRP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt91050
Q9UMX1-351-unknown	SSTAII...	351	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174336
Q9UMX1-351-unknown	SSTAII...	351	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174337
Q9UMX1-351-	SSTAII...	351		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UMX1-351-	SSTAII...	351		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...DSPLH	484	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)