Q9WTP6: Adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}

General Information

Protein names	- Adenylate kinase 2, mitochondrial {ECO:0000255\|HAMAP-Rule:MF_03168} - AK 2 {ECO:0000255\|HAMAP-Rule:MF_03168} - 2.7.4.3 {ECO:0000255\|HAMAP-Rule:MF_03168} - ATP-AMP transphosphorylase 2 {ECO:0000255\|HAMAP-Rule:MF_03168} - ATP:AMP phosphotransferase {ECO:0000255\|HAMAP-Rule:MF_03168} - Adenylate monophosphate kinase {ECO:0000255\|HAMAP-Rule:MF_03168}
Gene names	Ak2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9WTP6

7 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAPNVLASEP EIPKGIRAVL LGPPGAGKGT QAPKLAENFC VCHLATGDML RAMVASGSEL
        70         80         90        100        110        120
GKKLKATMDA GKLVSDEMVV ELIEKNLETP SCKNGFLLDG FPRTVRQAEM LDDLMEKRKE
       130        140        150        160        170        180
KLDSVIEFSI QDSLLIRRIT GRLIHPKSGR SYHEEFNPPK EPMKDDITGE PLIRRSDDNE
       190        200        210        220        230
KALKTRLEAY HTQTTPLVEY YRKRGIHCAI DASQTPDIVF ASILAAFSKA TCKDLVMFI

Isoforms

- Isoform 2 of Adenylate kinase 2, mitochondrial

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9WTP6-1-unknown	MAPNVL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78501
Q9WTP6-1-Acetylation	MAPNVL...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9WTP6-1-Acetylation	MAPNVL...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106477
Q9WTP6-2-Acetylation	MAPNVL...	1	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9WTP6-2-unknown	APNVLA...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9WTP6-2-unknown	APNVLA...	2		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111309
Q9WTP6-2-unknown	APNVLA...	2		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9WTP6-69-unknown	DAGKLV...	69		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q9WTP6-69-unknown	DAGKLV...	69		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt196465
Q9WTP6-107-Pyrrolidone carboxylic acid	QAEMLD...	107	pyrrolidone carboxylic acid-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q9WTP6-107-Pyrrolidone carboxylic acid	QAEMLD...	107	pyrrolidone carboxylic acid-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160780
Q9WTP6-129-unknown	SIQDSL...	129		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31327
Q9WTP6-129-unknown	SIQDSL...	129		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143851

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SVIEFS	128	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31327
...SVIEFS	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127095
...LVMFI	239	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	128	IEFS.\|.SIQD	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> KAD2_MOUSE @128

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)