Q9Y295: Developmentally-regulated GTP-binding protein 1

General Information

Protein names	- Developmentally-regulated GTP-binding protein 1 - DRG-1 - Neural precursor cell expressed developmentally down-regulated protein 3 - NEDD-3 - Translation factor GTPase DRG1 - TRAFAC GTPase DRG1 - 3.6.5.- {ECO:0000305\|PubMed:29915238}
Gene names	DRG1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y295

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSSTLAKIAE IEAEMARTQK NKATAHHLGL LKARLAKLRR ELITPKGGGG GGPGEGFDVA
        70         80         90        100        110        120
KTGDARIGFV GFPSVGKSTL LSNLAGVYSE VAAYEFTTLT TVPGVIRYKG AKIQLLDLPG
       130        140        150        160        170        180
IIEGAKDGKG RGRQVIAVAR TCNLILIVLD VLKPLGHKKI IENELEGFGI RLNSKPPNIG
       190        200        210        220        230        240
FKKKDKGGIN LTATCPQSEL DAETVKSILA EYKIHNADVT LRSDATADDL IDVVEGNRVY
       250        260        270        280        290        300
IPCIYVLNKI DQISIEELDI IYKVPHCVPI SAHHRWNFDD LLEKIWDYLK LVRIYTKPKG
       310        320        330        340        350        360
QLPDYTSPVV LPYSRTTVED FCMKIHKNLI KEFKYALVWG LSVKHNPQKV GKDHTLEDED

VIQIVKK

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y295-2-unknown	MSSTLA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y295-2-Acetylation	SSTLAK...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y295-2-Acetylation	SSTLAK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9Y295-2-Acetylation	SSTLAK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9Y295-174-unknown	SKPPNI...	174		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6932

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GIRLNS	173	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6932
	...QIVKK	367	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	173	RLNS.\|.SKPP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)