Q9Y2T4: Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

General Information

Protein names	- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform - IMYPNO1 - PP2A subunit B isoform B55-gamma - PP2A subunit B isoform PR55-gamma - PP2A subunit B isoform R2-gamma - PP2A subunit B isoform gamma
Gene names	PPP2R2C
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y2T4

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform - Isoform 3 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform - Isoform 4 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

Sequence View

        10         20         30         40         50         60
MGEDTDTRKI NHSFLRDHSY VTEADIISTV EFNHTGELLA TGDKGGRVVI FQREPESKNA
        70         80         90        100        110        120
PHSQGEYDVY STFQSHEPEF DYLKSLEIEE KINKIKWLPQ QNAAHSLLST NDKTIKLWKI
       130        140        150        160        170        180
TERDKRPEGY NLKDEEGKLK DLSTVTSLQV PVLKPMDLMV EVSPRRIFAN GHTYHINSIS
       190        200        210        220        230        240
VNSDCETYMS ADDLRINLWH LAITDRSFNI VDIKPANMED LTEVITASEF HPHHCNLFVY
       250        260        270        280        290        300
SSSKGSLRLC DMRAAALCDK HSKLFEEPED PSNRSFFSEI ISSVSDVKFS HSGRYMLTRD
       310        320        330        340        350        360
YLTVKVWDLN MEARPIETYQ VHDYLRSKLC SLYENDCIFD KFECAWNGSD SVIMTGAYNN
       370        380        390        400        410        420
FFRMFDRNTK RDVTLEASRE SSKPRAVLKP RRVCVGGKRR RDDISVDSLD FTKKILHTAW
       430        440
HPAENIIAIA ATNNLYIFQD KVNSDMH         10         20         30         40         50         60
MGEDTDTRKI NHSFLRDHSY VTEADIISTV EFNHTGELLA TGDKGGRVVI FQREPESKNA
        70         80         90        100        110        120
PHSQGEYDVY STFQSHEPEF DYLKSLEIEE KINKIKWLPQ QNAAHSLLST NDKTIKLWKI
       130        140        150        160        170        180
TERDKRPEGY NLKDEEGKLK DLSTVTSLQV PVLKPMDLMV EVSPRRIFAN GHTYHINSIS
       190        200        210        220        230        240
VNSDCETYMS ADDLRINLWH LAITDRSFNI VDIKPANMED LTEVITASEF HPHHCNLFVY
       250        260        270        280        290        300
SSSKGSLRLC DMRAAALCDK HSKLFEEPED PSNRSFFSEI ISSVSDVKFS HSGRYMLTRD
       310        320        330        340        350        360
YLTVKVWDLN MEARPIETYQ VHDYLRSKLC SLYENDCIFD KFECAWNGSD SVIMTGAYNN
       370        380        390        400        410        420
FFRMFDRNTK RDVTLEASRE SSKPRAVLKP RRVCVGGKRR RDDISVDSLD FTKKILHTAW
       430        440
HPAENIIAIA ATNNLYIFQD KVNSDMH         10         20         30         40         50         60
MGEDTDTRKI NHSFLRDHSY VTEADIISTV EFNHTGELLA TGDKGGRVVI FQREPESKNA
        70         80         90        100        110        120
PHSQGEYDVY STFQSHEPEF DYLKSLEIEE KINKIKWLPQ QNAAHSLLST NDKTIKLWKI
       130        140        150        160        170        180
TERDKRPEGY NLKDEEGKLK DLSTVTSLQV PVLKPMDLMV EVSPRRIFAN GHTYHINSIS
       190        200        210        220        230        240
VNSDCETYMS ADDLRINLWH LAITDRSFNI VDIKPANMED LTEVITASEF HPHHCNLFVY
       250        260        270        280        290        300
SSSKGSLRLC DMRAAALCDK HSKLFEEPED PSNRSFFSEI ISSVSDVKFS HSGRYMLTRD
       310        320        330        340        350        360
YLTVKVWDLN MEARPIETYQ VHDYLRSKLC SLYENDCIFD KFECAWNGSD SVIMTGAYNN
       370        380        390        400        410        420
FFRMFDRNTK RDVTLEASRE SSKPRAVLKP RRVCVGGKRR RDDISVDSLD FTKKILHTAW
       430        440
HPAENIIAIA ATNNLYIFQD KVNSDMH

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9Y2T4-1-unknown	MGEDTD...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Y2T4-75-unknown	SHEPEF...	75	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6934
Q9Y2T4-75-unknown	SHEPEF...	75	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139718
Q9Y2T4-75-unknown	SHEPEF...	75	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140480
Q9Y2T4-75-unknown	SHEPEF...	75	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140948

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YSTFQS	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6934
...YSTFQS	74	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122817
...YSTFQS	74	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123607
...YSTFQS	74	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124095
...NSDMH	447	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...NSDMH	447	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61377
...NSDMH	447	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61378
...NSDMH	447	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61376

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	74	TFQS.\|.SHEP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)