Q9Y3A3: MOB-like protein phocein

General Information

Protein names	- MOB-like protein phocein - 2C4D - Class II mMOB1 - Mob1 homolog 3 - Mob3 - Mps one binder kinase activator-like 3 - Preimplantation protein 3
Gene names	MOB4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y3A3

7 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of MOB-like protein phocein - Isoform 3 of MOB-like protein phocein

Sequence View

        10         20         30         40         50         60
MVMAEGTAVL RRNRPGTKAQ DFYNWPDESF DEMDSTLAVQ QYIQQNIRAD CSNIDKILEP
        70         80         90        100        110        120
PEGQDEGVWK YEHLRQFCLE LNGLAVKLQS ECHPDTCTQM TATEQWIFLC AAHKTPKECP
       130        140        150        160        170        180
AIDYTRHTLD GAACLLNSNK YFPSRVSIKE SSVAKLGSVC RRIYRIFSHA YFHHRQIFDE
       190        200        210        220
YENETFLCHR FTKFVMKYNL MSKDNLIVPI LEEEVQNSVS GESEA         10         20         30         40         50         60
MVMAEGTAVL RRNRPGTKAQ DFYNWPDESF DEMDSTLAVQ QYIQQNIRAD CSNIDKILEP
        70         80         90        100        110        120
PEGQDEGVWK YEHLRQFCLE LNGLAVKLQS ECHPDTCTQM TATEQWIFLC AAHKTPKECP
       130        140        150        160        170        180
AIDYTRHTLD GAACLLNSNK YFPSRVSIKE SSVAKLGSVC RRIYRIFSHA YFHHRQIFDE
       190        200        210        220
YENETFLCHR FTKFVMKYNL MSKDNLIVPI LEEEVQNSVS GESEA

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y3A3-1-unknown	MVMAEG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y3A3-2-	VMAEGT...	2			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q9Y3A3-2-	VMAEGT...	2			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9Y3A3-2-	VMAEGT...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9Y3A3-2-	VMAEGT...	2			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9Y3A3-2-	VMAEGT...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9Y3A3-2-	VMAEGT...	2			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q9Y3A3-2-unknown	VMAEGT...	2			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9Y3A3-2-unknown	VMAEGT...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9Y3A3-2-unknown	VMAEGT...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9Y3A3-4-acetylation	AEGTAV...	4	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9Y3A3-33-unknown	MDSTLA...	33		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85094
Q9Y3A3-35-	STLAVQ...	35			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9Y3A3-35-unknown	STLAVQ...	35		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2360
Q9Y3A3-35-unknown	STLAVQ...	35		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165201

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FDEMDS	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2360
...GESEA	225	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GESEA	225	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80712
...GESEA	225	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80713

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_HUMAN	34	EMDS.\|.STLA	inferred from experiment	unknown	MEROPS		Merops CASP3_HUMAN -> PHOCN_HUMAN @34

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)