Q9Y4P8: WD repeat domain phosphoinositide-interacting protein 2

General Information

Protein names	- WD repeat domain phosphoinositide-interacting protein 2 - WIPI-2 - WIPI49-like protein 2
Gene names	WIPI2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y4P8

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of WD repeat domain phosphoinositide-interacting protein 2 - Isoform 3 of WD repeat domain phosphoinositide-interacting protein 2 - Isoform 4 of WD repeat domain phosphoinositide-interacting protein 2 - Isoform 5 of WD repeat domain phosphoinositide-interacting protein 2 - Isoform 6 of WD repeat domain phosphoinositide-interacting protein 2

Sequence View

        10         20         30         40         50         60
MNLASQSGEA GAGQLLFANF NQDNTEVKGA SRAAGLGRRA VVWSLAVGSK SGYKFFSLSS
        70         80         90        100        110        120
VDKLEQIYEC TDTEDVCIVE RLFSSSLVAI VSLKAPRKLK VCHFKKGTEI CNYSYSNTIL
       130        140        150        160        170        180
AVKLNRQRLI VCLEESLYIH NIRDMKVLHT IRETPPNPAG LCALSINNDN CYLAYPGSAT
       190        200        210        220        230        240
IGEVQVFDTI NLRAANMIPA HDSPLAALAF DASGTKLATA SEKGTVIRVF SIPEGQKLFE
       250        260        270        280        290        300
FRRGVKRCVS ICSLAFSMDG MFLSASSNTE TVHIFKLETV KEKPPEEPTT WTGYFGKVLM
       310        320        330        340        350        360
ASTSYLPSQV TEMFNQGRAF ATVRLPFCGH KNICSLATIQ KIPRLLVGAA DGYLYMYNLD
       370        380        390        400        410        420
PQEGGECALM KQHRLDGSLE TTNEILDSAS HDCPLVTQTY GAAAGKGTYV PSSPTRLAYT
       430        440        450
DDLGAVGGAC LEDEASALRL DEDSEHPPMI LRTD         10         20         30         40         50         60
MNLASQSGEA GAGQLLFANF NQDNTEVKGA SRAAGLGRRA VVWSLAVGSK SGYKFFSLSS
        70         80         90        100        110        120
VDKLEQIYEC TDTEDVCIVE RLFSSSLVAI VSLKAPRKLK VCHFKKGTEI CNYSYSNTIL
       130        140        150        160        170        180
AVKLNRQRLI VCLEESLYIH NIRDMKVLHT IRETPPNPAG LCALSINNDN CYLAYPGSAT
       190        200        210        220        230        240
IGEVQVFDTI NLRAANMIPA HDSPLAALAF DASGTKLATA SEKGTVIRVF SIPEGQKLFE
       250        260        270        280        290        300
FRRGVKRCVS ICSLAFSMDG MFLSASSNTE TVHIFKLETV KEKPPEEPTT WTGYFGKVLM
       310        320        330        340        350        360
ASTSYLPSQV TEMFNQGRAF ATVRLPFCGH KNICSLATIQ KIPRLLVGAA DGYLYMYNLD
       370        380        390        400        410        420
PQEGGECALM KQHRLDGSLE TTNEILDSAS HDCPLVTQTY GAAAGKGTYV PSSPTRLAYT
       430        440        450
DDLGAVGGAC LEDEASALRL DEDSEHPPMI LRTD         10         20         30         40         50         60
MNLASQSGEA GAGQLLFANF NQDNTEVKGA SRAAGLGRRA VVWSLAVGSK SGYKFFSLSS
        70         80         90        100        110        120
VDKLEQIYEC TDTEDVCIVE RLFSSSLVAI VSLKAPRKLK VCHFKKGTEI CNYSYSNTIL
       130        140        150        160        170        180
AVKLNRQRLI VCLEESLYIH NIRDMKVLHT IRETPPNPAG LCALSINNDN CYLAYPGSAT
       190        200        210        220        230        240
IGEVQVFDTI NLRAANMIPA HDSPLAALAF DASGTKLATA SEKGTVIRVF SIPEGQKLFE
       250        260        270        280        290        300
FRRGVKRCVS ICSLAFSMDG MFLSASSNTE TVHIFKLETV KEKPPEEPTT WTGYFGKVLM
       310        320        330        340        350        360
ASTSYLPSQV TEMFNQGRAF ATVRLPFCGH KNICSLATIQ KIPRLLVGAA DGYLYMYNLD
       370        380        390        400        410        420
PQEGGECALM KQHRLDGSLE TTNEILDSAS HDCPLVTQTY GAAAGKGTYV PSSPTRLAYT
       430        440        450
DDLGAVGGAC LEDEASALRL DEDSEHPPMI LRTD         10         20         30         40         50         60
MNLASQSGEA GAGQLLFANF NQDNTEVKGA SRAAGLGRRA VVWSLAVGSK SGYKFFSLSS
        70         80         90        100        110        120
VDKLEQIYEC TDTEDVCIVE RLFSSSLVAI VSLKAPRKLK VCHFKKGTEI CNYSYSNTIL
       130        140        150        160        170        180
AVKLNRQRLI VCLEESLYIH NIRDMKVLHT IRETPPNPAG LCALSINNDN CYLAYPGSAT
       190        200        210        220        230        240
IGEVQVFDTI NLRAANMIPA HDSPLAALAF DASGTKLATA SEKGTVIRVF SIPEGQKLFE
       250        260        270        280        290        300
FRRGVKRCVS ICSLAFSMDG MFLSASSNTE TVHIFKLETV KEKPPEEPTT WTGYFGKVLM
       310        320        330        340        350        360
ASTSYLPSQV TEMFNQGRAF ATVRLPFCGH KNICSLATIQ KIPRLLVGAA DGYLYMYNLD
       370        380        390        400        410        420
PQEGGECALM KQHRLDGSLE TTNEILDSAS HDCPLVTQTY GAAAGKGTYV PSSPTRLAYT
       430        440        450
DDLGAVGGAC LEDEASALRL DEDSEHPPMI LRTD         10         20         30         40         50         60
MNLASQSGEA GAGQLLFANF NQDNTEVKGA SRAAGLGRRA VVWSLAVGSK SGYKFFSLSS
        70         80         90        100        110        120
VDKLEQIYEC TDTEDVCIVE RLFSSSLVAI VSLKAPRKLK VCHFKKGTEI CNYSYSNTIL
       130        140        150        160        170        180
AVKLNRQRLI VCLEESLYIH NIRDMKVLHT IRETPPNPAG LCALSINNDN CYLAYPGSAT
       190        200        210        220        230        240
IGEVQVFDTI NLRAANMIPA HDSPLAALAF DASGTKLATA SEKGTVIRVF SIPEGQKLFE
       250        260        270        280        290        300
FRRGVKRCVS ICSLAFSMDG MFLSASSNTE TVHIFKLETV KEKPPEEPTT WTGYFGKVLM
       310        320        330        340        350        360
ASTSYLPSQV TEMFNQGRAF ATVRLPFCGH KNICSLATIQ KIPRLLVGAA DGYLYMYNLD
       370        380        390        400        410        420
PQEGGECALM KQHRLDGSLE TTNEILDSAS HDCPLVTQTY GAAAGKGTYV PSSPTRLAYT
       430        440        450
DDLGAVGGAC LEDEASALRL DEDSEHPPMI LRTD

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
Q9Y4P8-1-unknown	MNLASQ...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y4P8-1-unknown	MNLASQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94561
Q9Y4P8-1-unknown	MNLASQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94563
Q9Y4P8-1-unknown	MNLASQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94565
Q9Y4P8-1-acetylation	MNLASQ...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q9Y4P8-1-acetylation	MNLASQ...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183286
Q9Y4P8-1-acetylation	MNLASQ...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183287
Q9Y4P8-1-acetylation	MNLASQ...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183288

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ILRTD	454	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ILRTD	454	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt90180
...ILRTD	454	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt90179
...ILRTD	454	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt90181
...ILRTD	454	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt90182
...ILRTD	454	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt90183

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)