Q9Y5X3: Sorting nexin-5

General Information

Protein names	- Sorting nexin-5
Gene names	SNX5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y5X3

3 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAVPELLQQ QEEDRSKLRS VSVDLNVDPS LQIDIPDALS ERDKVKFTVH TKTTLPTFQS
        70         80         90        100        110        120
PEFSVTRQHE DFVWLHDTLI ETTDYAGLII PPAPTKPDFD GPREKMQKLG EGEGSMTKEE
       130        140        150        160        170        180
FAKMKQELEA EYLAVFKKTV SSHEVFLQRL SSHPVLSKDR NFHVFLEYDQ DLSVRRKNTK
       190        200        210        220        230        240
EMFGGFFKSV VKSADEVLFT GVKEVDDFFE QEKNFLINYY NRIKDSCVKA DKMTRSHKNV
       250        260        270        280        290        300
ADDYIHTAAC LHSLALEEPT VIKKYLLKVA ELFEKLRKVE GRVSSDEDLK LTELLRYYML
       310        320        330        340        350        360
NIEAAKDLLY RRTKALIDYE NSNKALDKAR LKSKDVKLAE AHQQECCQKF EQLSESAKEE
       370        380        390        400
LINFKRKRVA AFRKNLIEMS ELEIKHARNN VSLLQSCIDL FKNN

Isoforms

- Isoform 2 of Sorting nexin-5

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y5X3-2-unknown	MAAVPE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y5X3-2-Acetylation	AAVPEL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y5X3-2-Acetylation	AAVPEL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9Y5X3-2-Acetylation	AAVPEL...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9Y5X3-2-Acetylation	AAVPEL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9Y5X3-2-Acetylation	AAVPEL...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q9Y5X3-178-	NTKEMF...	178			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...PTVIKK	263	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000406731
...IEAAKD	306	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000404448
...LFKNN	404	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...LFKNN	404		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LFKNN	404		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...LFKNN	404		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LFKNN	404		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)