TopFIND 4.0

Q9Y6L7: Tolloid-like protein 2

General Information

Protein names
- Tolloid-like protein 2
- 3.4.24.-
Gene names TLL2
Organism Homo sapiens
Protease Family M12.018
Protease ID M12.018
Chromosome location
UniProt ID Q9Y6L7

3

N-termini

1

C-termini

0

Cleavages

3

Substrates

Sequence

        10         20         30         40         50         60 
MPRATALGAL VSLLLLLPLP RGAGGLGERP DATADYSELD GEEGTEQQLE HYHDPCKAAV 
        70         80         90        100        110        120 
FWGDIALDED DLKLFHIDKA RDWTKQTVGA TGHSTGGLEE QASESSPDTT AMDTGTKEAG 
       130        140        150        160        170        180 
KDGRENTTLL HSPGTLHAAA KTFSPRVRRA TTSRTERIWP GGVIPYVIGG NFTGSQRAIF 
       190        200        210        220        230        240 
KQAMRHWEKH TCVTFIERTD EESFIVFSYR TCGCCSYVGR RGGGPQAISI GKNCDKFGIV 
       250        260        270        280        290        300 
AHELGHVVGF WHEHTRPDRD QHVTIIRENI QPGQEYNFLK MEAGEVSSLG ETYDFDSIMH 
       310        320        330        340        350        360 
YARNTFSRGV FLDTILPRQD DNGVRPTIGQ RVRLSQGDIA QARKLYKCPA CGETLQDTTG 
       370        380        390        400        410        420 
NFSAPGFPNG YPSYSHCVWR ISVTPGEKIV LNFTSMDLFK SRLCWYDYVE VRDGYWRKAP 
       430        440        450        460        470        480 
LLGRFCGDKI PEPLVSTDSR LWVEFRSSSN ILGKGFFAAY EATCGGDMNK DAGQIQSPNY 
       490        500        510        520        530        540 
PDDYRPSKEC VWRITVSEGF HVGLTFQAFE IERHDSCAYD YLEVRDGPTE ESALIGHFCG 
       550        560        570        580        590        600 
YEKPEDVKSS SNRLWMKFVS DGSINKAGFA ANFFKEVDEC SWPDHGGCEH RCVNTLGSYK 
       610        620        630        640        650        660 
CACDPGYELA ADKKMCEVAC GGFITKLNGT ITSPGWPKEY PTNKNCVWQV VAPAQYRISL 
       670        680        690        700        710        720 
QFEVFELEGN DVCKYDFVEV RSGLSPDAKL HGRFCGSETP EVITSQSNNM RVEFKSDNTV 
       730        740        750        760        770        780 
SKRGFRAHFF SDKDECAKDN GGCQHECVNT FGSYLCRCRN GYWLHENGHD CKEAGCAHKI 
       790        800        810        820        830        840 
SSVEGTLASP NWPDKYPSRR ECTWNISSTA GHRVKLTFNE FEIEQHQECA YDHLEMYDGP 
       850        860        870        880        890        900 
DSLAPILGRF CGSKKPDPTV ASGSSMFLRF YSDASVQRKG FQAVHSTECG GRLKAEVQTK 
       910        920        930        940        950        960 
ELYSHAQFGD NNYPSEARCD WVIVAEDGYG VELTFRTFEV EEEADCGYDY MEAYDGYDSS 
       970        980        990       1000       1010    
APRLGRFCGS GPLEEIYSAG DSLMIRFRTD DTINKKGFHA RYTSTKFQDA LHMKK

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 3 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LHMKK 1015 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates