P28300: Protein-lysine 6-oxidase
| Protein names | - Protein-lysine 6-oxidase - 1.4.3.13 {ECO:0000269|PubMed:26838787} - Lysyl oxidase |
|---|---|
| Gene names | LOX |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P28300 |
2
N-termini
2
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MRFAWTVLLL GPLQLCALVH CAPPAAGQQQ PPREPPAAPG AWRQQIQWEN NGQVFSLLSL
70 80 90 100 110 120
GSQYQPQRRR DPGAAVPGAA NASAQQPRTP ILLIRDNRTA AARTRTAGSS GVTAGRPRPT
130 140 150 160 170 180
ARHWFQAGYS TSRAREAGAS RAENQTAPGE VPALSNLRPP SRVDGMVGDD PYNPYKYSDD
190 200 210 220 230 240
NPYYNYYDTY ERPRPGGRYR PGYGTGYFQY GLPDLVADPY YIQASTYVQK MSMYNLRCAA
250 260 270 280 290 300
EENCLASTAY RADVRDYDHR VLLRFPQRVK NQGTSDFLPS RPRYSWEWHS CHQHYHSMDE
310 320 330 340 350 360
FSHYDLLDAN TQRRVAEGHK ASFCLEDTSC DYGYHRRFAC TAHTQGLSPG CYDTYGADID
370 380 390 400 410
CQWIDITDVK PGNYILKVSV NPSYLVPESD YTNNVVRCDI RYTGHHAYAS GCTISPY
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 3 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P28300-22-unknown | APPAAG... | 22 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P28300-169-unknown | DDPYNP... | 169 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P28300-169-unknown | DDPYNP... | 169 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31837 | |||
| P28300-169-unknown | DDPYNP... | 169 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31849 | |||
| P28300-169-unknown | DDPYNP... | 169 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC679 | |||
| P28300-169-unknown | DDPYNP... | 169 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...DGMVGD | 168 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31837 | |||
| ...DGMVGD | 168 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31849 | |||
| ...DGMVGD | 168 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC679 | |||
| ...TISPY | 417 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| TLL1_HUMAN | 168 | MVGD.|.DDPY | inferred from experiment | unknown | MEROPS | Trackman PC | Uzel MI et al.:Multiple bone morphogenetic pro... (M12.005) | 11313359, |
| TLL2_HUMAN | 168 | MVGD.|.DDPY | inferred from experiment | unknown | MEROPS | Trackman PC | Uzel MI et al.:Multiple bone morphogenetic pro... (M12.005) | 11313359, |
| BMP1_HUMAN | 168 | MVGD.|.DDPY | inferred from experiment | unknown | MEROPS | Trackman PC | Uzel MI et al.:Multiple bone morphogenetic pro... (M12.005) | 11313359, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|