Q9Z0N2: Eukaryotic translation initiation factor 2 subunit 3, Y-linked

General Information

Protein names	- Eukaryotic translation initiation factor 2 subunit 3, Y-linked - Eukaryotic translation initiation factor 2 subunit gamma, Y-linked - eIF-2-gamma Y - Spermatogonial proliferation factor {ECO:0000303\|PubMed:11528390} - Spy {ECO:0000303\|PubMed:11528390}
Gene names	Eif2s3y
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Z0N2

4 N-termini

2 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGGEAGVTL GQPHLSRQDL ATLDVTKLTP LSREIISRQA TINIGTIGHV AHGKSTVVKA
        70         80         90        100        110        120
ISGVHTVRFK NELERNITIK LGYANAKIYK LDDSSCPRPE CYRSCGSSTP DEFPSDIPGT
       130        140        150        160        170        180
KGNFRLVRHV SFVDCPGHDI LMATMLNGAA VMDAALLLIA GNESCPQPQT SEHLAAIEIM
       190        200        210        220        230        240
KLKHILILQN KIDLVKESQA KEQYEQILAF VQGTVAEGAP IIPISAQLKY NIEVVCEYIV
       250        260        270        280        290        300
KKIPVPLRDF TSEPRLIVIR SFDVNKPGCE VDDLKGGVAG GSILKGVLKV GQEIEVRPGI
       310        320        330        340        350        360
VSKDGEGKLM CKPIFSKIVS LFAEHNDLQY AAPGGLIGVG TKIDPTLCRA DRMVGQVLGA
       370        380        390        400        410        420
VGALPEIFTE LEISYFLLRR LLGVRTEGDK KAAKVQKLSK NEVLMVNIGS LSTGGRVSAV
       430        440        450        460        470
KADLGKIVLT NPVCTEVGEK IALSRRVEKH WRLIGWGQIR RGVTIKPTID DE

Isoforms

Sequence View

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9Z0N2-2-unknown	MAGGEA...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9Z0N2-2-unknown	MAGGEA...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Z0N2-2-Acetylation	AGGEAG...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Z0N2-2-Acetylation	AGGEAG...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9Z0N2-13-unknown	PHLSRQ...	13		inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q9Z0N2-405-unknown	MVNIGS...	405		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29448
Q9Z0N2-405-unknown	MVNIGS...	405		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31368

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KNEVLM	404	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29448
...KNEVLM	404	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31368
...TIDDE	472	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	404	EVLM.\|.MVNI	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	404	EVLM.\|.MVNI	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> IF2H_MOUSE @404

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

Q9Z0N2: Eukaryotic translation initiation factor 2 subunit 3, Y-linked

General Information

4

N-termini

2

C-termini

2

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates