Q9Z1F9: SUMO-activating enzyme subunit 2

General Information

Protein names	- SUMO-activating enzyme subunit 2 - 2.3.2.- - Anthracycline-associated resistance ARX - Ubiquitin-like 1-activating enzyme E1B - Ubiquitin-like modifier-activating enzyme 2
Gene names	Uba2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Z1F9

6 N-termini

5 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALSRGLPRE LAEAVSGGRV LVVGAGGIGC ELLKNLVLTG FSHIDLIDLD TIDVSNLNRQ
        70         80         90        100        110        120
FLFQKKHVGR SKAQVAKESV LQFHPQANIE AHHDSIMNPD YNVEFFRQFI LVMNALDNRA
       130        140        150        160        170        180
ARNHVNRMCL AADVPLIESG TAGYLGQVTT IKKGVTECYE CHPKPTQRTF PGCTIRNTPS
       190        200        210        220        230        240
EPIHCIVWAK YLFNQLFGEE DADQEVSPDR ADPEAAWEPT EAEARARASN EDGDIKRIST
       250        260        270        280        290        300
KEWAKSTGYD PVKLFTKLFK DDIRYLLTMD KLWRKRKPPV PLDWAEVQSQ GEANADQQNE
       310        320        330        340        350        360
PQLGLKDQQV LDVKSYASLF SKSIETLRVH LAEKGDGAEL IWDKDDPPAM DFVTSAANLR
       370        380        390        400        410        420
MHIFSMNMKS RFDIKSMAGN IIPAIATTNA VIAGLIVLEG LKILSGKIDQ CRTIFLNKQP
       430        440        450        460        470        480
NPRKKLLVPC ALDPPNTNCY VCASKPEVTV RLNVHKVTVL TLQDKIVKEK FAMVAPDVQI
       490        500        510        520        530        540
EDGKGTILIS SEEGETEANN PKKLSDFGIR NGSRLQADDF LQDYTLLINI LHSEDLGKDV
       550        560        570        580        590        600
EFEVVGDSPE KVGPKQAEDA AKSIANGSDD GAQPSTSTAQ EQDDVLIVDS DEEGPSNSTD
       610        620        630
CSGDDKARKR KLEENEAAST KKCRLEQMED PDDVIALD

Isoforms

Sequence View

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Evidence Codes:

Methodology:

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Evidence Names:

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Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9Z1F9-1-unknown	MALSRG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Z1F9-50-unknown	DTIDVS...	50	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31369
Q9Z1F9-117-unknown	DNRAAR...	117	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q9Z1F9-319-unknown	LFSKSI...	319	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34403
Q9Z1F9-353-unknown	VTSAAN...	353	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31370
Q9Z1F9-514-unknown	RLQADD...	514	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000135078

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DLIDLD	49	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31369
...IESGTA	141	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116605
...KSYASL	318	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34403
...PAMDFV	352	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31370
...VIALD	638	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	49	IDLD.\|.DTID	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> SAE2_MOUSE @49
MMP2_MOUSE	318	YASL.\|.LFSK	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	352	MDFV.\|.VTSA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> SAE2_MOUSE @352

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)