Q9Z1W4: Growth/differentiation factor 11
| Protein names | - Growth/differentiation factor 11 - GDF-11 - Bone morphogenetic protein 11 - BMP-11 |
|---|---|
| Gene names | Gdf11 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q9Z1W4 |
3
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MVLAAPLLLG FLLLALELRP RGEAAEGPAA AAAAAAAAAG VGGERSSRPA PSAPPEPDGC
70 80 90 100 110 120
PVCVWRQHSR ELRLESIKSQ ILSKLRLKEA PNISREVVKQ LLPKAPPLQQ ILDLHDFQGD
130 140 150 160 170 180
ALQPEDFLEE DEYHATTETV ISMAQETDPA VQTDGSPLCC HFHFSPKVMF TKVLKAQLWV
190 200 210 220 230 240
YLRPVPRPAT VYLQILRLKP LTGEGTAGGG GGGRRHIRIR SLKIELHSRS GHWQSIDFKQ
250 260 270 280 290 300
VLHSWFRQPQ SNWGIEINAF DPSGTDLAVT SLGPGAEGLH PFMELRVLEN TKRSRRNLGL
310 320 330 340 350 360
DCDEHSSESR CCRYPLTVDF EAFGWDWIIA PKRYKANYCS GQCEYMFMQK YPHTHLVQQA
370 380 390 400
NPRGSAGPCC TPTKMSPINM LYFNDKQQII YGKIPGMVVD RCGCS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q9Z1W4-21-unknown | RGEAAE... | 21 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q9Z1W4-120-unknown | DALQPE... | 120 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28314 | |||
| Q9Z1W4-297-unknown | NLGLDC... | 297 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q9Z1W4-297-unknown | NLGLDC... | 297 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34762 | |||
| Q9Z1W4-297-unknown | NLGLDC... | 297 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...HDFQGD | 119 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28314 | |||
| ...KRSRRN | 296 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34762 | |||
| ...RCGCS | 405 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| BMP1_MOUSE | 119 | FQGD.|.DALQ | inferred from experiment | unknown | MEROPS | Greenspan DS | Ge G et al.:GDF11 forms a bone morphogeneti... (M12.005) | 15988002, |
| PCSK5_MOUSE | 296 | SRRN.|.NLGL | inferred from experiment | unknown | MEROPS | Prat A | Essalmani R et al.:In vivo functions of the propro... (S08.076) | 18378898, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|