O00161: Synaptosomal-associated protein 23

General Information

Protein names	- Synaptosomal-associated protein 23 - SNAP-23 - Vesicle-membrane fusion protein SNAP-23
Gene names	SNAP23
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O00161

6 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDNLSSEEIQ QRAHQITDES LESTRRILGL AIESQDAGIK TITMLDEQKE QLNRIEEGLD
        70         80         90        100        110        120
QINKDMRETE KTLTELNKCC GLCVCPCNRT KNFESGKAYK TTWGDGGENS PCNVVSKQPG
       130        140        150        160        170        180
PVTNGQLQQP TTGAASGGYI KRITNDARED EMEENLTQVG SILGNLKDMA LNIGNEIDAQ
       190        200        210
NPQIKRITDK ADTNRDRIDI ANARAKKLID S

Isoforms

- Isoform SNAP-23b of Synaptosomal-associated protein 23

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O00161-1-unknown	MDNLSS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90137
O00161-1-Acetylation	MDNLSS...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O00161-1-Acetylation	MDNLSS...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O00161-1-Acetylation	MDNLSS...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
O00161-1-Acetylation	MDNLSS...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O00161-1-Acetylation	MDNLSS...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O00161-1-Acetylation	MDNLSS...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt103851
O00161-30-unknown	LAIESQ...	30		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171588
O00161-30-	LAIESQ...	30			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O00161-30-	LAIESQ...	30			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
O00161-30-	LAIESQ...	30			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O00161-125-	GQLQQP...	125			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O00161-125-	GQLQQP...	125			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O00161-125-	GQLQQP...	125			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
O00161-125-	GQLQQP...	125			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O00161-134-	AASGGY...	134			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O00161-134-	AASGGY...	134			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...KLIDS	211		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KLIDS	211		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...KLIDS	211	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...KLIDS	211	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt85755
...KLIDS	211		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KLIDS	211		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)