O08709: Peroxiredoxin-6

General Information

Protein names	- Peroxiredoxin-6 - 1.11.1.15 - 1-Cys peroxiredoxin - 1-Cys PRX - Acidic calcium-independent phospholipase A2 - aiPLA2 - 3.1.1.4 - Antioxidant protein 2 - Non-selenium glutathione peroxidase - NSGPx
Gene names	Prdx6
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O08709

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPGGLLLGDE APNFEANTTI GRIRFHDFLG DSWGILFSHP RDFTPVCTTE LGRAAKLAPE
        70         80         90        100        110        120
FAKRNVKLIA LSIDSVEDHL AWSKDINAYN GETPTEKLPF PIIDDKGRDL AILLGMLDPV
       130        140        150        160        170        180
EKDDNNMPVT ARVVFIFGPD KKLKLSILYP ATTGRNFDEI LRVVDSLQLT GTKPVATPVD
       190        200        210        220
WKKGESVMVV PTLSEEEAKQ CFPKGVFTKE LPSGKKYLRY TPQP

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O08709-2-unknown	PGGLLL...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O08709-2-unmodified	PGGLLL...	2		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
O08709-32-unknown	SWGILF...	32	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33132
O08709-116-unknown	MLDPVE...	116	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28641

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DFLGDS	31	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33132
...AILLGM	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28641
...YTPQP	224	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	31	LGDS.\|.SWGI	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	115	LLGM.\|.MLDP	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PRDX6_MOUSE @115

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)