O15228: Dihydroxyacetone phosphate acyltransferase

General Information

Protein names	- Dihydroxyacetone phosphate acyltransferase - DAP-AT - DHAP-AT - 2.3.1.42 - Acyl-CoA:dihydroxyacetonephosphateacyltransferase - Glycerone-phosphate O-acyltransferase
Gene names	GNPAT
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O15228

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MESSSSSNSY FSVGPTSPSA VVLLYSKELK KWDEFEDILE ERRHVSDLKF AMKCYTPLVY
        70         80         90        100        110        120
KGITPCKPID IKCSVLNSEE IHYVIKQLSK ESLQSVDVLR EEVSEILDEM SHKLRLGAIR
       130        140        150        160        170        180
FCAFTLSKVF KQIFSKVCVN EEGIQKLQRA IQEHPVVLLP SHRSYIDFLM LSFLLYNYDL
       190        200        210        220        230        240
PVPVIAAGMD FLGMKMVGEL LRMSGAFFMR RTFGGNKLYW AVFSEYVKTM LRNGYAPVEF
       250        260        270        280        290        300
FLEGTRSRSA KTLTPKFGLL NIVMEPFFKR EVFDTYLVPI SISYDKILEE TLYVYELLGV
       310        320        330        340        350        360
PKPKESTTGL LKARKILSEN FGSIHVYFGD PVSLRSLAAG RMSRSSYNLV PRYIPQKQSE
       370        380        390        400        410        420
DMHAFVTEVA YKMELLQIEN MVLSPWTLIV AVLLQNRPSM DFDALVEKTL WLKGLTQAFG
       430        440        450        460        470        480
GFLIWPDNKP AEEVVPASIL LHSNIASLVK DQVILKVDSG DSEVVDGLML QHITLLMCSA
       490        500        510        520        530        540
YRNQLLNIFV RPSLVAVALQ MTPGFRKEDV YSCFRFLRDV FADEFIFLPG NTLKDFEEGC
       550        560        570        580        590        600
YLLCKSEAIQ VTTKDILVTE KGNTVLEFLV GLFKPFVESY QIICKYLLSE EEDHFSEEQY
       610        620        630        640        650        660
LAAVRKFTSQ LLDQGTSQCY DVLSSDVQKN ALAACVRLGV VEKKKINNNC IFNVNEPATT
       670        680
KLEEMLGCKT PIGKPATAKL

Isoforms

- Isoform 2 of Dihydroxyacetone phosphate acyltransferase

Sequence View

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Physiological Relevance:

Evidence Codes:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O15228-1-unknown	MESSSS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O15228-12-	SVGPTS...	12		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O15228-12-	SVGPTS...	12		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
O15228-12-	SVGPTS...	12		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O15228-12-	SVGPTS...	12		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O15228-12-	SVGPTS...	12		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O15228-12-	SVGPTS...	12		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
O15228-12-	SVGPTS...	12		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O15228-12-	SVGPTS...	12		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
O15228-12-	SVGPTS...	12		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O15228-12-unknown	SVGPTS...	12		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O15228-12-unknown	SVGPTS...	12		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PISISY	283	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000402811
...DHFSEE	597	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411640
...ATAKL	680	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)