O35226: 26S proteasome non-ATPase regulatory subunit 4
Protein names | - 26S proteasome non-ATPase regulatory subunit 4 - 26S proteasome regulatory subunit RPN10 - 26S proteasome regulatory subunit S5A - Multiubiquitin chain-binding protein |
---|---|
Gene names | Psmd4 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | O35226 |
5
N-termini
4
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MVLESTMVCV DNSEYMRNGD FLPTRLQAQQ DAVNIVCHSK TRSNPENNVG LITLANDCEV
70 80 90 100 110 120
LTTLTPDTGR ILSKLHTVQP KGKITFCTGI RVAHLALKHR QGKNHKMRII AFVGSPVEDN
130 140 150 160 170 180
EKDLVKLAKR LKKEKVNVDI INFGEEEVNT EKLTAFVNTL NGKDGTGSHL VTVPPGPSLA
190 200 210 220 230 240
DALISSPILA GEGGAMLGLG ASDFEFGVDP SADPELALAL RVSMEEQRQR QEEEARRAAA
250 260 270 280 290 300
ASAAEAGIAT PGTEDSDDAL LKMTINQQEF GRPGLPDLSS MTEEEQIAYA MQMSLQGTEF
310 320 330 340 350 360
SQESADMDAS SAMDTSDPVK EEDDYDVMQD PEFLQSVLEN LPGVDPNNAA IRSVMGALAS
370
QATKDGKNDK KEEEKK
Isoforms
- Isoform Rpn10B of 26S proteasome non-ATPase regulatory subunit 4 - Isoform Rpn10C of 26S proteasome non-ATPase regulatory subunit 4 - Isoform Rpn10D of 26S proteasome non-ATPase regulatory subunit 4 - Isoform Rpn10E of 26S proteasome non-ATPase regulatory subunit 4Sequence View
10 20 30 40 50 60
MVLESTMVCV DNSEYMRNGD FLPTRLQAQQ DAVNIVCHSK TRSNPENNVG LITLANDCEV
70 80 90 100 110 120
LTTLTPDTGR ILSKLHTVQP KGKITFCTGI RVAHLALKHR QGKNHKMRII AFVGSPVEDN
130 140 150 160 170 180
EKDLVKLAKR LKKEKVNVDI INFGEEEVNT EKLTAFVNTL NGKDGTGSHL VTVPPGPSLA
190 200 210 220 230 240
DALISSPILA GEGGAMLGLG ASDFEFGVDP SADPELALAL RVSMEEQRQR QEEEARRAAA
250 260 270 280 290 300
ASAAEAGIAT PGTEDSDDAL LKMTINQQEF GRPGLPDLSS MTEEEQIAYA MQMSLQGTEF
310 320 330 340 350 360
SQESADMDAS SAMDTSDPVK EEDDYDVMQD PEFLQSVLEN LPGVDPNNAA IRSVMGALAS
370
QATKDGKNDK KEEEKK
10 20 30 40 50 60
MVLESTMVCV DNSEYMRNGD FLPTRLQAQQ DAVNIVCHSK TRSNPENNVG LITLANDCEV
70 80 90 100 110 120
LTTLTPDTGR ILSKLHTVQP KGKITFCTGI RVAHLALKHR QGKNHKMRII AFVGSPVEDN
130 140 150 160 170 180
EKDLVKLAKR LKKEKVNVDI INFGEEEVNT EKLTAFVNTL NGKDGTGSHL VTVPPGPSLA
190 200 210 220 230 240
DALISSPILA GEGGAMLGLG ASDFEFGVDP SADPELALAL RVSMEEQRQR QEEEARRAAA
250 260 270 280 290 300
ASAAEAGIAT PGTEDSDDAL LKMTINQQEF GRPGLPDLSS MTEEEQIAYA MQMSLQGTEF
310 320 330 340 350 360
SQESADMDAS SAMDTSDPVK EEDDYDVMQD PEFLQSVLEN LPGVDPNNAA IRSVMGALAS
370
QATKDGKNDK KEEEKK
10 20 30 40 50 60
MVLESTMVCV DNSEYMRNGD FLPTRLQAQQ DAVNIVCHSK TRSNPENNVG LITLANDCEV
70 80 90 100 110 120
LTTLTPDTGR ILSKLHTVQP KGKITFCTGI RVAHLALKHR QGKNHKMRII AFVGSPVEDN
130 140 150 160 170 180
EKDLVKLAKR LKKEKVNVDI INFGEEEVNT EKLTAFVNTL NGKDGTGSHL VTVPPGPSLA
190 200 210 220 230 240
DALISSPILA GEGGAMLGLG ASDFEFGVDP SADPELALAL RVSMEEQRQR QEEEARRAAA
250 260 270 280 290 300
ASAAEAGIAT PGTEDSDDAL LKMTINQQEF GRPGLPDLSS MTEEEQIAYA MQMSLQGTEF
310 320 330 340 350 360
SQESADMDAS SAMDTSDPVK EEDDYDVMQD PEFLQSVLEN LPGVDPNNAA IRSVMGALAS
370
QATKDGKNDK KEEEKK
10 20 30 40 50 60
MVLESTMVCV DNSEYMRNGD FLPTRLQAQQ DAVNIVCHSK TRSNPENNVG LITLANDCEV
70 80 90 100 110 120
LTTLTPDTGR ILSKLHTVQP KGKITFCTGI RVAHLALKHR QGKNHKMRII AFVGSPVEDN
130 140 150 160 170 180
EKDLVKLAKR LKKEKVNVDI INFGEEEVNT EKLTAFVNTL NGKDGTGSHL VTVPPGPSLA
190 200 210 220 230 240
DALISSPILA GEGGAMLGLG ASDFEFGVDP SADPELALAL RVSMEEQRQR QEEEARRAAA
250 260 270 280 290 300
ASAAEAGIAT PGTEDSDDAL LKMTINQQEF GRPGLPDLSS MTEEEQIAYA MQMSLQGTEF
310 320 330 340 350 360
SQESADMDAS SAMDTSDPVK EEDDYDVMQD PEFLQSVLEN LPGVDPNNAA IRSVMGALAS
370
QATKDGKNDK KEEEKK
Protein Neighborhood
Domains & Features
5 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
O35226-1-unknown | MVLEST... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
O35226-1-unknown | MVLEST... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86394 | |||
O35226-1-unknown | MVLEST... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86395 | |||
O35226-1-unknown | MVLEST... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86396 | |||
O35226-1-unknown | MVLEST... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86397 | |||
O35226-2-unknown | VLESTM... | 2 | N-TAILS | Overall CM. | auf dem Keller U.: A statistics-based platform for quantitative N-terminome... | 20305283 | |||
O35226-2-unknown | VLESTM... | 2 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160629 | |||
O35226-2-unknown | VLESTM... | 2 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160630 | |||
O35226-2-unknown | VLESTM... | 2 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160631 | |||
O35226-2-unknown | VLESTM... | 2 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160632 | |||
O35226-207-unknown | GVDPSA... | 207 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29507 | |||
O35226-207-unknown | GVDPSA... | 207 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt146787 | |||
O35226-207-unknown | GVDPSA... | 207 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt146788 | |||
O35226-207-unknown | GVDPSA... | 207 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt146789 | |||
O35226-207-unknown | GVDPSA... | 207 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt146790 | |||
O35226-337-unknown | VLENLP... | 337 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29512 | |||
O35226-337-unknown | VLENLP... | 337 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150730 | |||
O35226-339-unknown | ENLPGV... | 339 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28651 | |||
O35226-339-unknown | ENLPGV... | 339 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150795 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...SDFEFG | 206 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29507 | |||
...SDFEFG | 206 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130108 | |||
...SDFEFG | 206 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130109 | |||
...SDFEFG | 206 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130111 | |||
...SDFEFG | 206 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130112 | |||
...EFLQSV | 336 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29512 | |||
...EFLQSV | 336 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt134128 | |||
...LQSVLE | 338 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28651 | |||
...LQSVLE | 338 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt134197 | |||
...EEEKK | 376 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...EEEKK | 376 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt82012 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 206 | FEFG.|.GVDP | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> PSMD4_MOUSE @206 | ||
CATE_MOUSE | 336 | LQSV.|.VLEN | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> PSMD4_MOUSE @336 | ||
CATD_MOUSE | 338 | SVLE.|.ENLP | inferred from experiment | unknown | MEROPS | Merops CATD_MOUSE -> PSMD4_MOUSE @338 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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