O43592: Exportin-T

General Information

Protein names	- Exportin-T - Exportin(tRNA) - tRNA exportin
Gene names	XPOT
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43592

2 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDEQALLGLN PNADSDFRQR ALAYFEQLKI SPDAWQVCAE ALAQRTYSDD HVKFFCFQVL
        70         80         90        100        110        120
EHQVKYKYSE LTTVQQQLIR ETLISWLQAQ MLNPQPEKTF IRNKAAQVFA LLFVTEYLTK
       130        140        150        160        170        180
WPKFFFDILS VVDLNPRGVD LYLRILMAID SELVDRDVVH TSEEARRNTL IKDTMREQCI
       190        200        210        220        230        240
PNLVESWYQI LQNYQFTNSE VTCQCLEVVG AYVSWIDLSL IANDRFINML LGHMSIEVLR
       250        260        270        280        290        300
EEACDCLFEV VNKGMDPVDK MKLVESLCQV LQSAGFFSID QEEDVDFLAR FSKLVNGMGQ
       310        320        330        340        350        360
SLIVSWSKLI KNGDIKNAQE ALQAIETKVA LMLQLLIHED DDISSNIIGF CYDYLHILKQ
       370        380        390        400        410        420
LTVLSDQQKA NVEAIMLAVM KKLTYDEEYN FENEGEDEAM FVEYRKQLKL LLDRLAQVSP
       430        440        450        460        470        480
ELLLASVRRV FSSTLQNWQT TRFMEVEVAI RLLYMLAEAL PVSHGAHFSG DVSKASALQD
       490        500        510        520        530        540
MMRTLVTSGV SSYQHTSVTL EFFETVVRYE KFFTVEPQHI PCVLMAFLDH RGLRHSSAKV
       550        560        570        580        590        600
RSRTAYLFSR FVKSLNKQMN PFIEDILNRI QDLLELSPPE NGHQSLLSSD DQLFIYETAG
       610        620        630        640        650        660
VLIVNSEYPA ERKQALMRNL LTPLMEKFKI LLEKLMLAQD EERQASLADC LNHAVGFASR
       670        680        690        700        710        720
TSKAFSNKQT VKQCGCSEVY LDCLQTFLPA LSCPLQKDIL RSGVRTFLHR MIICLEEEVL
       730        740        750        760        770        780
PFIPSASEHM LKDCEAKDLQ EFIPLINQIT AKFKIQVSPF LQQMFMPLLH AIFEVLLRPA
       790        800        810        820        830        840
EENDQSAALE KQMLRRSYFA FLQTVTGSGM SEVIANQGAE NVERVLVTVI QGAVEYPDPI
       850        860        870        880        890        900
AQKTCFIILS KLVELWGGKD GPVGFADFVY KHIVPACFLA PLKQTFDLAD AQTVLALSEC
       910        920        930        940        950        960
AVTLKTIHLK RGPECVQYLQ QEYLPSLQVA PEIIQEFCQA LQQPDAKVFK NYLKVFFQRA

KP

Isoforms

Sequence View

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Evidence Codes:

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Protein Neighborhood

Domains & Features

2 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O43592-1-Acetylation	MDEQAL...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O43592-1-Acetylation	MDEQAL...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O43592-1-Acetylation	MDEQAL...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
O43592-1-Acetylation	MDEQAL...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O43592-1-Acetylation	MDEQAL...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O43592-807-unknown	GSGMSE...	807		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5170

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...CFQVLE	60	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000441376
...TNSEVT	201	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000383722
...SGVRTF	706	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444345
...LQTVTG	806	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5170
...QRAKP	962	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	806	TVTG.\|.GSGM	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)