TopFIND 4.0

O43895: Xaa-Pro aminopeptidase 2

General Information

Protein names
- Xaa-Pro aminopeptidase 2
- 3.4.11.9 {ECO:0000269|PubMed:15361070}
- Aminoacylproline aminopeptidase
- Membrane-bound aminopeptidase P
- Membrane-bound APP
- Membrane-bound AmP
- mAmP
- X-Pro aminopeptidase 2
Gene names XPNPEP2
Organism Homo sapiens
Protease Family M24.005
Protease ID M24.005
Chromosome location
UniProt ID O43895

1

N-termini

1

C-termini

0

Cleavages

4

Substrates

Sequence

        10         20         30         40         50         60 
MARAHWGCCP WLVLLCACAW GHTKPVDLGG QDVRNCSTNP PYLPVTVVNT TMSLTALRQQ 
        70         80         90        100        110        120 
MQTQNLSAYI IPGTDAHMNE YIGQHDERRA WITGFTGSAG TAVVTMKKAA VWTDSRYWTQ 
       130        140        150        160        170        180 
AERQMDCNWE LHKEVGTTPI VTWLLTEIPA GGRVGFDPFL LSIDTWESYD LALQGSNRQL 
       190        200        210        220        230        240 
VSITTNLVDL VWGSERPPVP NQPIYALQEA FTGSTWQEKV SGVRSQMQKH QKVPTAVLLS 
       250        260        270        280        290        300 
ALEETAWLFN LRASDIPYNP FFYSYTLLTD SSIRLFANKS RFSSETLSYL NSSCTGPMCV 
       310        320        330        340        350        360 
QIEDYSQVRD SIQAYSLGDV RIWIGTSYTM YGIYEMIPKE KLVTDTYSPV MMTKAVKNSK 
       370        380        390        400        410        420 
EQALLKASHV RDAVAVIRYL VWLEKNVPKG TVDEFSGAEI VDKFRGEEQF SSGPSFETIS 
       430        440        450        460        470        480 
ASGLNAALAH YSPTKELNRK LSSDEMYLLD SGGQYWDGTT DITRTVHWGT PSAFQKEAYT 
       490        500        510        520        530        540 
RVLIGNIDLS RLIFPAATSG RMVEAFARRA LWDAGLNYGH GTGHGIGNFL CVHEWPVGFQ 
       550        560        570        580        590        600 
SNNIAMAKGM FTSIEPGYYK DGEFGIRLED VALVVEAKTK YPGSYLTFEV VSFVPYDRNL 
       610        620        630        640        650        660 
IDVSLLSPEH LQYLNRYYQT IREKVGPELQ RRQLLEEFEW LQQHTEPLAA RAPDTASWAS 
       670    
VLVVSTLAIL GWSV

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 4 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O43895-22-unknown HTKPVD... 22 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TEPLAA 649 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates