O75127: Pentatricopeptide repeat-containing protein 1, mitochondrial

General Information

Protein names	- Pentatricopeptide repeat-containing protein 1, mitochondrial
Gene names	PTCD1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75127

3 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDFVRLARLF ARARPMGLFI LQHLDPCRAR WAGGREGLMR PMWAPFSSSS SQLPLGQERQ
        70         80         90        100        110        120
ENTGSLGSDP SHSNSTATQE EDEEEEESFG TLSDKYSSRR LFRKSAAQFH NLRFGERRDE
       130        140        150        160        170        180
QMEPEPKLWR GRRNTPYWYF LQCKHLIKEG KLVEALDLFE RQMLKEERLQ PMESNYTVLI
       190        200        210        220        230        240
GGCGRVGYLK KAFNLYNQMK KRDLEPSDAT YTALFNVCAE SPWKDSALQS ALKLRQQLQA
       250        260        270        280        290        300
KNFELNLKTY HALLKMAAKC ADLRMCLDVF KEIIHKGHVV TEETFSFLLM GCIQDKKTGF
       310        320        330        340        350        360
RYALQVWRLM LSLGLQPSRD SYNLLLVAAR DCGLGDPQVA SELLLKPREE ATVLQPPVSR
       370        380        390        400        410        420
QRPRRTAQAK AGNLMSAMLH VEALERQLFL EPSQALGPPE PPEARVPGKA QPEVDTKAEP
       430        440        450        460        470        480
SHTAALTAVA LKPPPVELEV NLLTPGAVPP TVVSFGTVTT PADRLALIGG LEGFLSKMAE
       490        500        510        520        530        540
HRQQPDIRTL TLLAEVVESG SPAESLLLAL LDEHQVEADL TFFNTLVRKK SKLGDLEGAK
       550        560        570        580        590        600
ALLPVLAKRG LVPNLQTFCN LAIGCHRPKD GLQLLTDMKK SQVTPNTHIY SALINAAIRK
       610        620        630        640        650        660
LNYTYLISIL KDMKQNRVPV NEVVIRQLEF AAQYPPTFDR YQGKNTYLEK IDGFRAYYKQ
       670        680        690        700
WLTVMPAEET PHPWQKFRTK PQGDQDTGKE ADDGCALGGR

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O75127-1-unknown	MDFVRL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75127-47-	SSSSSQ...	47		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O75127-47-	SSSSSQ...	47		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O75127-47-	SSSSSQ...	47		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O75127-47-	SSSSSQ...	47		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O75127-47-	SSSSSQ...	47		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
O75127-47-	SSSSSQ...	47		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O75127-47-	SSSSSQ...	47		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O75127-47-unknown	SSSSSQ...	47		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FRKSAA	106	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401600
...FLQCKH	144	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000408059
...ERQMLK	164	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000390530
...ALGGR	700	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)