O75521: Enoyl-CoA delta isomerase 2, mitochondrial

General Information

Protein names	- Enoyl-CoA delta isomerase 2, mitochondrial - 5.3.3.8 - DRS-1 - Delta(3),delta(2)-enoyl-CoA isomerase - D3,D2-enoyl-CoA isomerase - Diazepam-binding inhibitor-related protein 1 - DBI-related protein 1 - Dodecenoyl-CoA isomerase - Hepatocellular carcinoma-associated antigen 88 - Peroxisomal 3,2-trans-enoyl-CoA isomerase - pECI - Renal carcinoma antigen NY-REN-1
Gene names	ECI2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75521

8 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAMAYLAWRL ARRSCPSSLQ VTSFPVVQLH MNRTAMRASQ KDFENSMNQV KLLKKDPGNE
        70         80         90        100        110        120
VKLKLYALYK QATEGPCNMP KPGVFDLINK AKWDAWNALG SLPKEAARQN YVDLVSSLSP
       130        140        150        160        170        180
SLESSSQVEP GTDRKSTGFE TLVVTSEDGI TKIMFNRPKK KNAINTEMYH EIMRALKAAS
       190        200        210        220        230        240
KDDSIITVLT GNGDYYSSGN DLTNFTDIPP GGVEEKAKNN AVLLREFVGC FIDFPKPLIA
       250        260        270        280        290        300
VVNGPAVGIS VTLLGLFDAV YASDRATFHT PFSHLGQSPE GCSSYTFPKI MSPAKATEML
       310        320        330        340        350        360
IFGKKLTAGE ACAQGLVTEV FPDSTFQKEV WTRLKAFAKL PPNALRISKE VIRKREREKL
       370        380        390
HAVNAEECNV LQGRWLSDEC TNAVVNFLSR KSKL

Isoforms

- Isoform 2 of Enoyl-CoA delta isomerase 2, mitochondrial

Sequence View

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

8 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O75521-31-unknown	MNRTAM...	31	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000369468
O75521-31-unknown	MNRTAM...	31	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000354737
O75521-31-unknown	MNRTAM...	31	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000420309
O75521-36-unknown	MRASQK...	36	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73596
O75521-38-unknown	ASQKDF...	38	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168102
O75521-38-	ASQKDF...	38		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O75521-38-	ASQKDF...	38		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O75521-38-	ASQKDF...	38		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
O75521-38-	ASQKDF...	38		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O75521-38-	ASQKDF...	38		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O75521-39-unknown	SQKDFE...	39	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75521-39-unknown	SQKDFE...	39	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115365
O75521-115-	VSSLSP...	115		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O75521-115-unknown	VSSLSP...	115	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169986
O75521-168-unknown	MYHEIM...	168	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000406969
O75521-168-unknown	MYHEIM...	168	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt131284

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YHEIMR	173	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417459
...YHEIMR	173	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt111460
...RKSKL	394	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...RKSKL	394	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69214

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)