O75888: Tumor necrosis factor ligand superfamily member 13
Protein names | - Tumor necrosis factor ligand superfamily member 13 - A proliferation-inducing ligand - APRIL - TNF- and APOL-related leukocyte expressed ligand 2 - TALL-2 - TNF-related death ligand 1 - TRDL-1 - CD256 |
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Gene names | TNFSF13 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | O75888 |
3
N-termini
2
C-termini
5
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MPASSPFLLA PKGPPGNMGG PVREPALSVA LWLSWGAALG AVACAMALLT QQTELQSLRR
70 80 90 100 110 120
EVSRLQGTGG PSQNGEGYPW QSLPEQSSDA LEAWENGERS RKRRAVLTQK QKKQHSVLHL
130 140 150 160 170 180
VPINATSKDD SDVTEVMWQP ALRRGRGLQA QGYGVRIQDA GVYLLYSQVL FQDVTFTMGQ
190 200 210 220 230 240
VVSREGQGRQ ETLFRCIRSM PSHPDRAYNS CYSAGVFHLH QGDILSVIIP RARAKLNLSP
250
HGTFLGFVKL
Isoforms
- Isoform Beta of Tumor necrosis factor ligand superfamily member 13 - Isoform Gamma of Tumor necrosis factor ligand superfamily member 13 - Isoform 4 of Tumor necrosis factor ligand superfamily member 13 - Isoform 5 of Tumor necrosis factor ligand superfamily member 13Sequence View
10 20 30 40 50 60
MPASSPFLLA PKGPPGNMGG PVREPALSVA LWLSWGAALG AVACAMALLT QQTELQSLRR
70 80 90 100 110 120
EVSRLQGTGG PSQNGEGYPW QSLPEQSSDA LEAWENGERS RKRRAVLTQK QKKQHSVLHL
130 140 150 160 170 180
VPINATSKDD SDVTEVMWQP ALRRGRGLQA QGYGVRIQDA GVYLLYSQVL FQDVTFTMGQ
190 200 210 220 230 240
VVSREGQGRQ ETLFRCIRSM PSHPDRAYNS CYSAGVFHLH QGDILSVIIP RARAKLNLSP
250
HGTFLGFVKL
10 20 30 40 50 60
MPASSPFLLA PKGPPGNMGG PVREPALSVA LWLSWGAALG AVACAMALLT QQTELQSLRR
70 80 90 100 110 120
EVSRLQGTGG PSQNGEGYPW QSLPEQSSDA LEAWENGERS RKRRAVLTQK QKKQHSVLHL
130 140 150 160 170 180
VPINATSKDD SDVTEVMWQP ALRRGRGLQA QGYGVRIQDA GVYLLYSQVL FQDVTFTMGQ
190 200 210 220 230 240
VVSREGQGRQ ETLFRCIRSM PSHPDRAYNS CYSAGVFHLH QGDILSVIIP RARAKLNLSP
250
HGTFLGFVKL
10 20 30 40 50 60
MPASSPFLLA PKGPPGNMGG PVREPALSVA LWLSWGAALG AVACAMALLT QQTELQSLRR
70 80 90 100 110 120
EVSRLQGTGG PSQNGEGYPW QSLPEQSSDA LEAWENGERS RKRRAVLTQK QKKQHSVLHL
130 140 150 160 170 180
VPINATSKDD SDVTEVMWQP ALRRGRGLQA QGYGVRIQDA GVYLLYSQVL FQDVTFTMGQ
190 200 210 220 230 240
VVSREGQGRQ ETLFRCIRSM PSHPDRAYNS CYSAGVFHLH QGDILSVIIP RARAKLNLSP
250
HGTFLGFVKL
10 20 30 40 50 60
MPASSPFLLA PKGPPGNMGG PVREPALSVA LWLSWGAALG AVACAMALLT QQTELQSLRR
70 80 90 100 110 120
EVSRLQGTGG PSQNGEGYPW QSLPEQSSDA LEAWENGERS RKRRAVLTQK QKKQHSVLHL
130 140 150 160 170 180
VPINATSKDD SDVTEVMWQP ALRRGRGLQA QGYGVRIQDA GVYLLYSQVL FQDVTFTMGQ
190 200 210 220 230 240
VVSREGQGRQ ETLFRCIRSM PSHPDRAYNS CYSAGVFHLH QGDILSVIIP RARAKLNLSP
250
HGTFLGFVKL
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 5 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
O75888-1-unknown | MPASSP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92594 | |||
O75888-1-unknown | MPASSP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92595 | |||
O75888-1-unknown | MPASSP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92596 | |||
O75888-18-unknown | MGGPVR... | 18 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92597 | |||
O75888-18-unknown | MGGPVR... | 18 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt106041 | |||
O75888-18-unknown | MGGPVR... | 18 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt106042 | |||
O75888-18-unknown | MGGPVR... | 18 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt106043 | |||
O75888-105-unknown | AVLTQK... | 105 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
O75888-105-unknown | AVLTQK... | 105 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC26950 | |||
O75888-105-unknown | AVLTQK... | 105 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27248 | |||
O75888-105-unknown | AVLTQK... | 105 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC26536 | |||
O75888-105-unknown | AVLTQK... | 105 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC26807 | |||
O75888-105-unknown | AVLTQK... | 105 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27099 | |||
O75888-105-unknown | AVLTQK... | 105 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt115866 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...SRKRRA | 104 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC26950 | |||
...SRKRRA | 104 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27248 | |||
...SRKRRA | 104 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC26536 | |||
...SRKRRA | 104 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC26807 | |||
...SRKRRA | 104 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27099 | |||
...SRKRRA | 104 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125838 | |||
...SRKRRA | 104 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt154423 | |||
...GFVKL | 250 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...GFVKL | 250 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88215 | |||
...GFVKL | 250 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88214 | |||
...GFVKL | 250 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88212 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
PCSK5_HUMAN | 104 | KRRA.|.AVLT | inferred from experiment | unknown | MEROPS | Strongin AY | Remacle AG et al.:Substrate cleavage analysis of ... (S08.071) | 18505722, |
PCSK7_HUMAN | 104 | KRRA.|.AVLT | inferred from experiment | unknown | MEROPS | Strongin AY | Remacle AG et al.:Substrate cleavage analysis of ... (S08.071) | 18505722, |
NEC2_HUMAN | 104 | KRRA.|.AVLT | inferred from experiment | unknown | MEROPS | Strongin AY | Remacle AG et al.:Substrate cleavage analysis of ... (S08.071) | 18505722, |
PCSK4_HUMAN | 104 | KRRA.|.AVLT | inferred from experiment | unknown | MEROPS | Strongin AY | Remacle AG et al.:Substrate cleavage analysis of ... (S08.071) | 18505722, |
PCSK6_HUMAN | 104 | KRRA.|.AVLT | inferred from experiment | unknown | MEROPS | Strongin AY | Remacle AG et al.:Substrate cleavage analysis of ... (S08.071) | 18505722, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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