O75934: Pre-mRNA-splicing factor SPF27

General Information

Protein names	- Pre-mRNA-splicing factor SPF27 - Breast carcinoma-amplified sequence 2 - DNA amplified in mammary carcinoma 1 protein - Spliceosome-associated protein SPF 27
Gene names	BCAS2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75934

7 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGTGLVAGE VVVDALPYFD QGYEAPGVRE AAAALVEEET RRYRPTKNYL SYLTAPDYSA
        70         80         90        100        110        120
FETDIMRNEF ERLAARQPIE LLSMKRYELP APSSGQKNDI TAWQECVNNS MAQLEHQAVR
       130        140        150        160        170        180
IENLELMSQH GCNAWKVYNE NLVHMIEHAQ KELQKLRKHI QDLNWQRKNM QLTAGSKLRE
       190        200        210        220
MESNWVSLVS KNYEIERTIV QLENEIYQIK QQHGEANKEN IRQDF

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O75934-2-unknown	MAGTGL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75934-2-Acetylation	AGTGLV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75934-2-Acetylation	AGTGLV...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O75934-2-Acetylation	AGTGLV...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O75934-15-unknown	ALPYFD...	15			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O75934-15-	ALPYFD...	15			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
O75934-15-	ALPYFD...	15			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
O75934-15-	ALPYFD...	15			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O75934-15-	ALPYFD...	15			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
O75934-15-	ALPYFD...	15			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O75934-15-	ALPYFD...	15			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O75934-15-	ALPYFD...	15			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
O75934-15-	ALPYFD...	15			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O75934-15-	ALPYFD...	15			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
O75934-15-	ALPYFD...	15			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O75934-24-	EAPGVR...	24			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O75934-24-	EAPGVR...	24			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O75934-32-	AAALVE...	32			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O75934-110-	SMAQLE...	110			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...IRQDF	225	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)