O76076: WNT1-inducible-signaling pathway protein 2
| Protein names | - WNT1-inducible-signaling pathway protein 2 - WISP-2 - CCN family member 5 - Connective tissue growth factor-like protein - CTGF-L - Connective tissue growth factor-related protein 58 |
|---|---|
| Gene names | WISP2 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | O76076 |
4
N-termini
4
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MRGTPKTHLL AFSLLCLLSK VRTQLCPTPC TCPWPPPRCP LGVPLVLDGC GCCRVCARRL
70 80 90 100 110 120
GEPCDQLHVC DASQGLVCQP GAGPGGRGAL CLLAEDDSSC EVNGRLYREG ETFQPHCSIR
130 140 150 160 170 180
CRCEDGGFTC VPLCSEDVRL PSWDCPHPRR VEVLGKCCPE WVCGQGGGLG TQPLPAQGPQ
190 200 210 220 230 240
FSGLVSSLPP GVPCPEWSTA WGPCSTTCGL GMATRVSNQN RFCRLETQRR LCLSRPCPPS
250
RGRSPQNSAF
Isoforms
- Isoform 2 of WNT1-inducible-signaling pathway protein 2Sequence View
10 20 30 40 50 60
MRGTPKTHLL AFSLLCLLSK VRTQLCPTPC TCPWPPPRCP LGVPLVLDGC GCCRVCARRL
70 80 90 100 110 120
GEPCDQLHVC DASQGLVCQP GAGPGGRGAL CLLAEDDSSC EVNGRLYREG ETFQPHCSIR
130 140 150 160 170 180
CRCEDGGFTC VPLCSEDVRL PSWDCPHPRR VEVLGKCCPE WVCGQGGGLG TQPLPAQGPQ
190 200 210 220 230 240
FSGLVSSLPP GVPCPEWSTA WGPCSTTCGL GMATRVSNQN RFCRLETQRR LCLSRPCPPS
250
RGRSPQNSAF
Protein Neighborhood
Domains & Features
4 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| O76076-24-unknown | QLCPTP... | 24 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| O76076-178-unknown | GPQFSG... | 178 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21429 | |||
| O76076-184-unknown | LVSSLP... | 184 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21430 | |||
| O76076-216-unknown | VSNQNR... | 216 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15826 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...PLPAQG | 177 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21429 | |||
| ...PQFSGL | 183 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21430 | |||
| ...GMATRV | 215 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15826 | |||
| ...QNSAF | 250 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MMP14_HUMAN | 177 | PAQG.|.GPQF | inferred from experiment | unknown | MEROPS | Seth A | Overall CM et al.:Protease degradomics: mass spec... (M10.014) | 15255181, |
| MMP14_HUMAN | 183 | FSGL.|.LVSS | inferred from experiment | unknown | MEROPS | Seth A | Overall CM et al.:Protease degradomics: mass spec... (M10.014) | 15255181, |
| KLK12_HUMAN | 215 | ATRV.|.VSNQ | inferred from experiment | unknown | MEROPS | Courty Y | Guillon-Munos A et al.:Kallikrein-related peptidase 12... (S01.020) | 21628462, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|