O88342: WD repeat-containing protein 1

General Information

Protein names	- WD repeat-containing protein 1 - Actin-interacting protein 1 - AIP1
Gene names	Wdr1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O88342

7 N-termini

5 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPYEIKKVFA SLPQVERGVS KILGGDPKGD HFLYTNGKCV ILRNIDNPAI ADIYTEHAHQ
        70         80         90        100        110        120
VVVAKYAPSG FYIASGDISG KLRIWDTTQK EHLLKYEYQP FAGKIKDIAW TEDSKRIAVV
       130        140        150        160        170        180
GEGREKFGAV FLWDTGSSVG EITGHNKVIN SVDIKQTRPY RLATGSDDNC AAFFEGPPFK
       190        200        210        220        230        240
FKFTIGDHSR FVNCVRFSPD GNRFATASAD GQIFIYDGKT GEKVCALGES KAHDGGIYAI
       250        260        270        280        290        300
SWSPDSTHLL SASGDKTSKI WDVNVNSVVS TFPMGSNVLD QQLGCLWQKD HLLSISLSGY
       310        320        330        340        350        360
INYLDKNNPS KPLRVIKGHS KSIQCLTVHR NGGKSYIYSG SHDGHINYWD SETGENDSFS
       370        380        390        400        410        420
GKGHTNQVSR MTVNESEQLV SCSMDDTVRY TNLTLRDYSG QGVVKLDVQP KCVAVGPGGY
       430        440        450        460        470        480
TVVVCIGQIV LLKDQKKCFS IDNPGYEPEV VAVHPGGDTV AVGGTDGNVR VYSILASTLK
       490        500        510        520        530        540
DEGKLLEAKG PVTDVAYSHD GAFLAVCDAS KVVTVFSVAD GYSENNVFYG HHAKIVCLAW
       550        560        570        580        590        600
SPDNEHFASG GMDMMVYVWT LSDPETKVKI QDAHRLHHVS SLAWLDEHTL VTTSHDASVK

EWTITY

Isoforms

Sequence View

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Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 5 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O88342-2-unknown	PYEIKK...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O88342-2-unknown	PYEIKK...	2	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
O88342-2-unmodified	PYEIKK...	2		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
O88342-5-unknown	IKKVFA...	5	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33167
O88342-33-unknown	LYTNGK...	33	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29575
O88342-72-unknown	YIASGD...	72	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28678
O88342-72-unknown	YIASGD...	72	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29576
O88342-73-unknown	IASGDI...	73	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29577
O88342-380-unknown	VSCSMD...	380	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29578

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KGDHFL	32	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29575
...APSGFY	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28678
...APSGFY	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29576
...PSGFYI	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29577
...ESEQLV	379	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29578
...WTITY	606	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	4	PYEI.\|.IKKV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	32	DHFL.\|.LYTN	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> WDR1_MOUSE @32
CATD_MOUSE	71	SGFY.\|.YIAS	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> WDR1_MOUSE @71
CATE_MOUSE	71	SGFY.\|.YIAS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> WDR1_MOUSE @71
CATE_MOUSE	72	GFYI.\|.IASG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> WDR1_MOUSE @72
CATE_MOUSE	379	EQLV.\|.VSCS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> WDR1_MOUSE @379

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)