O88456: Calpain small subunit 1

General Information

Protein names	- Calpain small subunit 1 - CSS1 - Calcium-activated neutral proteinase small subunit - CANP small subunit - Calcium-dependent protease small subunit - CDPS - Calcium-dependent protease small subunit 1 - Calpain regulatory subunit
Gene names	Capns1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O88456

3 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MFLVNSFLKG GGGGGGGGGL GGGLGNVLGG LISGAAGGGG GGGGGGMGLG GGGGGGGTAM
        70         80         90        100        110        120
RILGGVISAI SEAAAQYNPE PPPPRSHYSN IEANESEEVR QFRKLFVQLA GDDMEVSATE
       130        140        150        160        170        180
LMNILNKVVT RHPDLKTDGF GIDTCRSMVA VMDSDTTGKL GFEEFKYLWN NIKKWQAIYK
       190        200        210        220        230        240
RFDTDRSGTI GSHELPGAFE AAGFHLNEHL YSMIIRRYAD ESGNMDFDNF ISCLVRLDAM
       250        260
FRAFKSLDKN GTGQIQVNIQ EWLQLTMYS

Isoforms

Sequence View

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Physiological Relevance:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
O88456-1-Acetylation	MFLVNS...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O88456-70-unknown	ISEAAA...	70		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28679
O88456-91-unknown	IEANES...	91		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33168

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GVISAI	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28679
...SHYSNI	90	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33168
...DAMFRA	242	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117951
...LTMYS	269	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	69	ISAI.\|.ISEA	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> CPNS1_MOUSE @69
MMP2_MOUSE	90	YSNI.\|.IEAN	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)