O95336: 6-phosphogluconolactonase

General Information

Protein names	- 6-phosphogluconolactonase - 6PGL - 3.1.1.31
Gene names	PGLS
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95336

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAPAPGLIS VFSSSQELGA ALAQLVAQRA ACCLAGARAR FALGLSGGSL VSMLARELPA
        70         80         90        100        110        120
AVAPAGPASL ARWTLGFCDE RLVPFDHAES TYGLYRTHLL SRLPIPESQV ITINPELPVE
       130        140        150        160        170        180
EAAEDYAKKL RQAFQGDSIP VFDLLILGVG PDGHTCSLFP DHPLLQEREK IVAPISDSPK
       190        200        210        220        230        240
PPPQRVTLTL PVLNAARTVI FVATGEGKAA VLKRILEDQE ENPLPAALVQ PHTGKLCWFL
       250
DEAAARLLTV PFEKHSTL

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
O95336-2-unknown	MAAPAP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95336-2-Acetylation	AAPAPG...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95336-2-Acetylation	AAPAPG...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O95336-65-unknown	AGPASL...	65		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000471951
O95336-177-unknown	DSPKPP...	177		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18329

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VAPISD	176	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18329
...TGEGKA	208	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472345
...KHSTL	258	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	176	PISD.\|.DSPK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)