TopFIND 4.0

P01137: Transforming growth factor beta-1 proprotein

General Information

Protein names
- Transforming growth factor beta-1 proprotein
- Latency-associated peptide {ECO:0000305|PubMed:2982829, ECO:0000305|PubMed:3162913, ECO:0000305|PubMed:7737999, ECO:0000305|PubMed:8471846}
- LAP
- Transforming growth factor beta-1 {ECO:0000305|PubMed:2982829, ECO:0000305|PubMed:3162913, ECO:0000305|PubMed:7737999, ECO:0000305|PubMed:8471846}
- TGF-beta-1
Gene names TGFB1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P01137

2

N-termini

2

C-termini

7

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPPSGLRLLL LLLPLLWLLV LTPGRPAAGL STCKTIDMEL VKRKRIEAIR GQILSKLRLA 
        70         80         90        100        110        120 
SPPSQGEVPP GPLPEAVLAL YNSTRDRVAG ESAEPEPEPE ADYYAKEVTR VLMVETHNEI 
       130        140        150        160        170        180 
YDKFKQSTHS IYMFFNTSEL REAVPEPVLL SRAELRLLRL KLKVEQHVEL YQKYSNNSWR 
       190        200        210        220        230        240 
YLSNRLLAPS DSPEWLSFDV TGVVRQWLSR GGEIEGFRLS AHCSCDSRDN TLQVDINGFT 
       250        260        270        280        290        300 
TGRRGDLATI HGMNRPFLLL MATPLERAQH LQSSRHRRAL DTNYCFSSTE KNCCVRQLYI 
       310        320        330        340        350        360 
DFRKDLGWKW IHEPKGYHAN FCLGPCPYIW SLDTQYSKVL ALYNQHNPGA SAAPCCVPQA 
       370        380        390    
LEPLPIVYYV GRKPKVEQLS NMIVRSCKCS 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 7 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)